Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure (Q31013659)

28 June 2017

title

Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure (English)

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28 June 2017

Shen K

1

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28 June 2017

Keng YF

2

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28 June 2017

Wu L

3

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28 June 2017

Guo XL

4

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28 June 2017

Lawrence DS

5

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28 June 2017

Zhang ZY

6

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28 June 2017

language of work or name

English

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publication date

2 October 2001

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Journal of Biological Chemistry

28 June 2017

published in

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28 June 2017

volume

276

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28 June 2017

issue

50

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28 June 2017

page(s)

47311-47319

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Protein tyrosine phosphatases: prospects for therapeutics

28 June 2017

cites work

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21 January 2018

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Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin

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Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor

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Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo

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The nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage

21 January 2018

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A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b

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21 January 2018

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VHR and PTP1 protein phosphatases exhibit remarkably different active site specificities toward low molecular weight nonpeptidic substrates

21 January 2018

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Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

21 January 2018

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Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation

21 January 2018

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Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.

21 January 2018

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Substrate specificity of the protein tyrosine phosphatases

21 January 2018

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Protein tyrosine phosphatase substrate specificity: size and phosphotyrosine positioning requirements in peptide substrates

21 January 2018

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An immunological approach reveals biological differences between the two NDF/heregulin receptors, ErbB-3 and ErbB-4.

21 January 2018

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The single sulfur to oxygen substitution in the active site nucleophile of the Yersinia protein-tyrosine phosphatase leads to substantial structural and functional perturbations

21 January 2018

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21 January 2018

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Affinity selection from peptide libraries to determine substrate specificity of protein tyrosine phosphatases

21 January 2018

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21 January 2018

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PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes

21 January 2018

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21 January 2018

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Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action

21 January 2018

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The Noncatalytic C-terminal Segment of the T Cell Protein Tyrosine Phosphatase Regulates Activity via an Intramolecular Mechanism

21 January 2018

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Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein expression

21 January 2018

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Overexpression of the tyrosine phosphatase PTP1B is associated with human ovarian carcinomas

21 January 2018

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Assessment of protein-tyrosine phosphatase 1B substrate specificity using "inverse alanine scanning"

21 January 2018

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Light-Induced Electron-Transfer Reactions Involving the Tris(2,2'-Bipyridine)Ruthenium Dication and Related Complexes. 3. Improved Synthesis of 2,2'-Bipyridine-4,4'-Dicarboxylic Acid and Photoreduction of Water by Bis(2,2'-Bipyridine)(2,2'-Bipyridine

21 January 2018

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Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR

21 January 2018

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Potent and highly selective inhibitors of the protein tyrosine phosphatase 1B

21 January 2018

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Potent Inhibition of Insulin Receptor Dephosphorylation by a Hexamer Peptide Containing the Phosphotyrosyl Mimetic F2Pmp

21 January 2018

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Why is phosphonodifluoromethyl phenylalanine a more potent inhibitory moiety than phosphonomethyl phenylalanine toward protein-tyrosine phosphatases?

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M106568200

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28 June 2017

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