Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity (Q31038912)

28 June 2017

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity (English)

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28 June 2017

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14

Guy Salvesen

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28 June 2017

Aaron D Schimmer

1

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28 June 2017

Kate Welsh

2

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28 June 2017

Clemencia Pinilla

3

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28 June 2017

Zhiliang Wang

4

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28 June 2017

Maryla Krajewska

5

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28 June 2017

Marie-Josee Bonneau

6

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28 June 2017

Irene M Pedersen

7

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28 June 2017

Shinichi Kitada

8

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28 June 2017

Fiona L Scott

9

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28 June 2017

Beatrice Bailly-Maitre

10

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28 June 2017

Gennadi Glinsky

11

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28 June 2017

Dominick Scudiero

12

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28 June 2017

Edward Sausville

13

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28 June 2017

Adel Nefzi

15

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28 June 2017

John M Ostresh

16

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28 June 2017

Richard A Houghten

17

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28 June 2017

John C Reed

18

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28 June 2017

1 January 2004

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5

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1

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28 June 2017

25-35

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Death receptors: signaling and modulation

28 June 2017

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Role of XIAP in the malignant phenotype of transitional cell cancer (TCC) and therapeutic activity of XIAP antisense oligonucleotides against multidrug-resistant TCC in vitro.

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

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7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Proliferation, cell cycle and apoptosis in cancer

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients.

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7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Characterization of XIAP-deficient mice

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

HBXIP functions as a cofactor of survivin in apoptosis suppression

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

"Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity

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7 January 2021

Advances in the use of synthetic combinatorial chemistry: mixture-based libraries

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7 January 2021

The Survivin saga goes in vivo

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Structural basis for the inhibition of caspase-3 by XIAP

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Biochemical characteristics of caspases-3, -6, -7, and -8

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Caspase-9 can be activated without proteolytic processing

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Reprieval from execution: the molecular basis of caspase inhibition

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

A single BIR domain of XIAP sufficient for inhibiting caspases

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Caspases: enemies within

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Development and characterization of nonpeptidic small molecule inhibitors of the XIAP/caspase-3 interaction

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900332-5

7 January 2021

10.1016/S1535-6108(03)00332-5

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DOI

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28 June 2017

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