Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE). (Q31044261)

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English	Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE).	scientific article

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scholarly article

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19 January 2020

Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE) (English)

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19 January 2020

experimental autoimmune encephalomyelitis

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based on heuristic

inferred from title

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based on heuristic

inferred from title

7

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19 January 2020

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Derek J Abbott

1

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19 January 2020

J Lori Blanchfield

2

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19 January 2020

David A Martinson

3

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19 January 2020

Sean C Russell

4

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19 January 2020

Najla Taslim

5

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19 January 2020

Alan D Curtis

6

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19 January 2020

publication date

30 December 2011

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19 January 2020

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19 January 2020

12

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19 January 2020

72

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19 January 2020

Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo

1 reference

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21 June 2018

Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity

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21 June 2018

Current concepts in the neuropathology and pathogenesis of multiple sclerosis

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21 June 2018

Dendritic cells in networks of immunological tolerance.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

How tolerogenic dendritic cells induce regulatory T cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

GM-CSF-induced, bone-marrow-derived dendritic cells can expand natural Tregs and induce adaptive Tregs by different mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

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21 June 2018

Inflammation, demyelination, and degeneration - recent insights from MS pathology.

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21 June 2018

Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link

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21 June 2018

T-cell based immunotherapy in experimental autoimmune encephalomyelitis and multiple sclerosis

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21 June 2018

A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APC

1 reference

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21 June 2018

Neurodegeneration in autoimmune CNS inflammation

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21 June 2018

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

1 reference

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21 June 2018

Neuroinflammation responses and neurodegeneration in multiple sclerosis

1 reference

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21 June 2018

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

1 reference

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21 June 2018

Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models

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21 June 2018

T-cells in multiple sclerosis

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21 June 2018

Myeloid-derived suppressor cells as regulators of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Lessons from multiple sclerosis: models, concepts, observations

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21 June 2018

CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Tuning microenvironments: induction of regulatory T cells by dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Strategies for treating autoimmunity: novel insights from experimental myasthenia gravis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Regulatory T cells induced by GM-CSF suppress ongoing experimental myasthenia gravis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines

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21 June 2018

Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease

1 reference

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21 June 2018

Multiple sclerosis: a complicated picture of autoimmunity.

1 reference

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21 June 2018

Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

A fusion protein consisting of IL-16 and the encephalitogenic peptide of myelin basic protein constitutes an antigen-specific tolerogenic vaccine that inhibits experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF.

1 reference

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21 June 2018

Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of beta cells

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21 June 2018

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

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21 June 2018

Molecular Mimicry Revisited: Gut Bacteria and Multiple Sclerosis

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21 June 2018

High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells

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21 June 2018

Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo

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21 June 2018

The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis

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21 June 2018

Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer

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21 June 2018

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

1 reference

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21 June 2018

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

1 reference

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21 June 2018

Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo

1 reference

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21 June 2018

Role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma. II. Down-regulation of macrophage-mediated cytotoxicity by tumor-derived granulocyte-macrophage colony-stimulating factor.

1 reference

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21 June 2018

The N- and C-terminal boundaries of myelin basic protein determinants required for encephalitogenic and proliferative responses of Lewis rat T cells☆☆☆

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

21 June 2018

Experimental autoimmune encephalomyelitis in Lewis rats: IFN-beta acts as a tolerogenic adjuvant for induction of neuroantigen-dependent tolerance.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-72

21 January 2018

Autoantigen-pulsed dendritic cells induce tolerance to experimental allergic encephalomyelitis (EAE) in Lewis rats

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-72

21 January 2018

Self-immobilizing recombinant antibody fragments for immunoaffinity chromatography: generic, parallel, and scalable protein purification

1 reference

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21 January 2018

IL-4 responsive CD4+ T cells specific for myelin basic protein: IL-2 confers a prolonged postactivation refractory phase

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-72

21 January 2018

Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

25 November 2018

IL-2/neuroantigen fusion proteins as antigen-specific tolerogens in experimental autoimmune encephalomyelitis (EAE): correlation of T cell-mediated antigen presentation and tolerance induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

25 November 2018

Selective induction of dendritic cells using granulocyte macrophage-colony stimulating factor, but not fms-like tyrosine kinase receptor 3-ligand, activates thyroglobulin-specific CD4+/CD25+ T cells and suppresses experimental autoimmune thyroiditis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261124

25 November 2018

Role of GM-CSF in tolerance induction by mobilized hematopoietic progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mimicry in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GM-CSF induces bone marrow precursors of NOD mice to skew into tolerogenic dendritic cells that protect against diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonotypic heterogeneity of Lewis rat T cells specific for the encephalitogenic 68-86 region of myelin basic protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10-producing CD4+CD25+ regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mimicry in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial stroma programs hematopoietic stem cells to differentiate into regulatory dendritic cells through IL-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of experimental autoimmune myasthenia gravis by granulocyte-macrophage colony-stimulating factor is associated with an expansion of FoxP3+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-neuroantigen fusion proteins: new tools for modulation of myelin basic protein (MBP)-specific T cell responses in experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22208499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2172-12-72

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22208499%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22208499%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22208499%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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