BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production (Q31047574)

23 September 2017

BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production (English)

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23 September 2017

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5

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23 September 2017

Nicholas W Morrell

7

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author name string

John E S Park

1

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23 September 2017

Dongmin Shao

2

1 reference

23 September 2017

Paul D Upton

3

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23 September 2017

Patricia Desouza

4

1 reference

23 September 2017

Rachel J Davies

6

1 reference

23 September 2017

Mark J D Griffiths

8

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23 September 2017

Stephen J Wort

9

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23 September 2017

language of work or name

English

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publication date

27 January 2012

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23 September 2017

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23 September 2017

7

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23 September 2017

1

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23 September 2017

e30075

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Creative Commons Attribution 4.0 International

23 September 2017

start time

27 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension

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Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells

21 June 2018

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Endothelin receptor antagonism and cancer

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Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity

21 June 2018

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Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

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Bone morphogenetic protein-9 is a circulating vascular quiescence factor

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IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation

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Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cells

21 June 2018

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The selectivity of protein kinase inhibitors: a further update

21 June 2018

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BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes

21 June 2018

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

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Pulmonary hypertension due to BMPR2 mutation: a new paradigm for tissue remodeling?

21 June 2018

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Drug Insight: endothelin-receptor antagonists for pulmonary arterial hypertension in systemic rheumatic diseases

21 June 2018

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Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

21 June 2018

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ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Evidence for the presence of endothelin ETA receptors in endothelial cells in situ on the aortic side of porcine aortic valve

21 June 2018

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Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

21 June 2018

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Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

21 January 2018

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Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy

21 January 2018

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Signaling molecules in nonfamilial pulmonary hypertension

21 January 2018

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p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage.

21 January 2018

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Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

21 January 2018

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Deletion of Endothelial Cell Endothelin B Receptors Does Not Affect Blood Pressure or Sensitivity to Salt

21 January 2018

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Endothelin-1 in the lungs of patients with pulmonary hypertension

21 January 2018

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Bone morphogenic protein-9 stimulates endothelin-1 release from human pulmonary microvascular endothelial cells: a potential mechanism for elevated ET-1 levels in pulmonary arterial hypertension.

21 January 2018

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Endothelin-1 enhances cell migration via matrix metalloproteinase-9 up-regulation in brain astrocytes.

25 November 2018

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Proliferative stimulation of the vascular Endothelin-1 axis in vitro and ex vivo by infection with Chlamydia pneumoniae.

25 November 2018

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Bosentan therapy for pulmonary arterial hypertension

25 November 2018

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12 December 2020

Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation

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12 December 2020

Localization of endothelin receptors in bleomycin-induced pulmonary fibrosis in the rat

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12 December 2020

Transforming growth factor-beta induces endothelin-1 expression through activation of the Smad signaling pathway

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12 December 2020

Signaling by ALK5 mediates TGF-beta-induced ET-1 expression in endothelial cells: a role for migration and proliferation

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12 December 2020

Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia

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12 December 2020

Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats

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12 December 2020

Endothelin receptor expression in idiopathic pulmonary arterial hypertension: effect of bosentan and epoprostenol treatment

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12 December 2020

10.1371/JOURNAL.PONE.0030075

Identifiers

DOI

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23 September 2017

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23 September 2017

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