Transmutation of human glutathione transferase A2-2 with peroxidase activity into an efficient steroid isomerase (Q31060519)

28 June 2017

Transmutation of human glutathione transferase A2-2 with peroxidase activity into an efficient steroid isomerase (English)

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28 June 2017

Par L Pettersson

1

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28 June 2017

Ann-Sofie Johansson

series ordinal

2

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28 June 2017

Bengt Mannervik

series ordinal

3

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28 June 2017

language of work or name

English

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publication date

21 May 2002

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Journal of Biological Chemistry

28 June 2017

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28 June 2017

277

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28 June 2017

30019-30022

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28 June 2017

33

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Protein folds, functions and evolution

28 June 2017

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https://api.crossref.org/works/10.1074%2FJBC.M204485200

Estimating the number of protein folds and families from complete genome data

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204485200

Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Converting trypsin to chymotrypsin: the role of surface loops

21 January 2018

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Computational method to reduce the search space for directed protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Enzyme-like proteins by computational design

21 January 2018

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Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Combinatorial and computational challenges for biocatalyst design

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204485200

Protein evolution by molecular breeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

The role of glutathione in the isomerization of delta 5-androstene-3,17-dione catalyzed by human glutathione transferase A1-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Active-site residues governing high steroid isomerase activity in human glutathione transferase A3-3

21 January 2018

1 reference

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The C-terminal region of human glutathione transferase A1-1 affects the rate of glutathione binding and the ionization of the active-site Tyr9.

21 January 2018

1 reference

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The role of human glutathione S-transferases hGSTA1-1 and hGSTA2-2 in protection against oxidative stress

21 January 2018

1 reference

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Disorder-to-order transition of the active site of human class Pi glutathione transferase, GST P1-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Selective catalysis of elementary steps by Asp-99 and Tyr-14 of 3-Oxo-delta(5)-steroid isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Conformational changes: how small is big enough?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities

21 January 2018

1 reference

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Small-molecule metabolism: an enzyme mosaic

21 January 2018

1 reference

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Human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase: purification from mitochondria and kinetic profiles, biophysical characterization of the purified mitochondrial and microsomal enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

Redesign of substrate-selectivity determining modules of glutathione transferase A1-1 installs high catalytic efficiency with toxic alkenal products of lipid peroxidation

21 January 2018

1 reference

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Reengineering the glutathione S-transferase scaffold: a rational design strategy pays off.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204485200

21 January 2018

Identifiers

DOI

10.1074/JBC.M204485200

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28 June 2017

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