T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading (Q31066837)

28 June 2017

T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading (English)

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28 June 2017

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Patrick A Ott

1

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28 June 2017

Marcus T Dittrich

2

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28 June 2017

Bernhard A Herzog

3

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28 June 2017

Robert Guerkov

4

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28 June 2017

Peter A Gottlieb

5

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28 June 2017

Amy L Putnam

6

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28 June 2017

Ivana Durinovic-Bello

7

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28 June 2017

Bernhard O Boehm

8

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28 June 2017

Magdalena Tary-Lehmann

9

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28 June 2017

Paul V Lehmann

10

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28 June 2017

1 July 2004

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Journal of Clinical Immunology

28 June 2017

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28 June 2017

24

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28 June 2017

4

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28 June 2017

327-339

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Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays

28 June 2017

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12 December 2020

Direct visualization of cytokine-producing recall antigen-specific CD4 memory T cells in healthy individuals and HIV patients.

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12 December 2020

Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

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12 December 2020

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

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12 December 2020

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

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12 December 2020

Maturation of the humoral autoimmune response to epitopes of GAD in preclinical childhood type 1 diabetes

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12 December 2020

Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop fo

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12 December 2020

The Karlsburg type 1 diabetes risk study of a normal schoolchild population: association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals

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12 December 2020

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

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12 December 2020

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

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12 December 2020

Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes

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12 December 2020

T-cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM, post-onset IDDM patients and control subjects

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12 December 2020

Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription

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12 December 2020

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients

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12 December 2020

Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects

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12 December 2020

Shifting T-cell activation thresholds in autoimmunity and determinant spreading

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12 December 2020

Modern concepts for the prediction of type 1 diabetes

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12 December 2020

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

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12 December 2020

Dominance and crypticity of T cell antigenic determinants

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12 December 2020

Immunization with the larger isoform of mouse glutamic acid decarboxylase (GAD67) prevents autoimmune diabetes in NOD mice

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12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

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12 December 2020

Enumerating autoreactive T cells in peripheral blood: a big step in diabetes prediction

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12 December 2020

T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects

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12 December 2020

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

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12 December 2020

Strategies for epitope analysis using peptide synthesis.

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12 December 2020

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

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12 December 2020

Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells

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12 December 2020

Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus

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12 December 2020

HLA-DR, DQ and DP typing using PCR amplification and immobilized probes

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12 December 2020

Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes

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12 December 2020

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

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12 December 2020

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

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12 December 2020

Endogenous myelin basic protein inactivates the high avidity T cell repertoire

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12 December 2020

Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein.

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12 December 2020

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

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12 December 2020

Pathogenicity of T cells responsive to diverse cryptic epitopes of myelin basic protein in the Lewis rat

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12 December 2020

Evolution of the T-cell repertoire during the course of experimental immune-mediated demyelinating diseases

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12 December 2020

Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes

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12 December 2020

Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone

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12 December 2020

Does GAD have a unique role in triggering IDDM?

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12 December 2020

Autoantigens IA-2 and GAD in Type I (insulin-dependent) diabetes

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12 December 2020

T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes

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12 December 2020

The naive repertoire of human T helper cells specific for gp120, the envelope glycoprotein of HIV

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12 December 2020

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

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12 December 2020

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

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12 December 2020

Evolution of the enzyme-linked immunosorbent spot assay for post-transplant alloreactivity as a potentially useful immune monitoring tool.

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12 December 2020

Differential presentation of glutamic acid decarboxylase 65 (GAD65) T cell epitopes among HLA-DRB1*0401-positive individuals

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12 December 2020

GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.

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12 December 2020

Early development and spreading of autoantibodies to epitopes of IA-2 and their association with progression to type 1 diabetes

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12 December 2020

10.1023/B:JOCI.0000029120.77824.41

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28 June 2017

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