Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors (Q31126839)

2 November 2017

Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors (English)

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2 November 2017

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Michael J Breen

1

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2 November 2017

Diarmuid M Moran

2

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2 November 2017

Wenzhe Liu

3

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2 November 2017

Xiaoke Huang

4

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2 November 2017

Calvin P H Vary

5

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2 November 2017

Raymond C Bergan

6

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2 November 2017

language of work or name

English

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publication date

13 August 2013

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2 November 2017

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2 November 2017

8

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2 November 2017

8

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2 November 2017

e72407

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Creative Commons Attribution 4.0 International

2 November 2017

start time

13 August 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration

21 June 2018

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Dietary genistein inhibits metastasis of human prostate cancer in mice

21 June 2018

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BMP-6 over-expression in prostate cancer is associated with increased Id-1 protein and a more invasive phenotype

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Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells

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BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo

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Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway

21 June 2018

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21 June 2018

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Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling

21 June 2018

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21 June 2018

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Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors.

21 June 2018

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21 June 2018

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CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells

21 June 2018

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Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells

21 June 2018

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Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex

21 June 2018

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TGF-beta receptor function in the endothelium.

21 June 2018

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Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis

21 June 2018

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Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells

21 June 2018

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Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins

21 June 2018

1 reference

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Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain

21 June 2018

1 reference

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Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

21 June 2018

1 reference

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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

21 June 2018

1 reference

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Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

21 June 2018

1 reference

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The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 June 2018

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Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 June 2018

1 reference

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Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Identification of a binding site on the type II activin receptor for activin and inhibin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycan.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Endoglin modulates cellular responses to TGF-beta 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Human-restricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

Whole-mount prostate sections reveal differential endoglin expression in stromal, epithelial, and endothelial cells with the development of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension

21 January 2018

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Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone

21 January 2018

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Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

Bone morphogenetic protein-10 suppresses the growth and aggressiveness of prostate cancer cells through a Smad independent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0072407

Role of bone morphogenetic proteins in human prostate cancer pathogenesis and development of bone metastases: immunohistochemical study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742533

Endoglin (CD105) is expressed on immature blood vessels and is a marker for survival in prostate cancer

25 November 2018

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12 December 2020

p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion

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12 December 2020

Signal transduction by bone morphogenetic proteins

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12 December 2020

Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in prostatic adenocarcinoma

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12 December 2020

Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer

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12 December 2020

The role of the TGF-β coreceptor endoglin in cancer

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12 December 2020

10.1371/JOURNAL.PONE.0072407

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DOI

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2 November 2017

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2 November 2017

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