Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase. (Q31136147)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655019%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase (English)

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1 November 2019

5

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1 November 2019

author name string

LeAnn J Godderz

1

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1 November 2019

Negar S Rahman

2

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1 November 2019

George M Risinger

3

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1 November 2019

Janeen L Arbuckle

4

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1 November 2019

language of work or name

English

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publication date

1 April 2003

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1 November 2019

published in

Nucleic Acids Research

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1 November 2019

volume

31

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1 November 2019

issue

7

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1 November 2019

page(s)

2014-2023

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RAG1-DNA binding in V(D)J recombination. Specificity and DNA-induced conformational changes revealed by fluorescence and CD spectroscopy

1 November 2019

cites work

1 reference

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A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals

21 June 2018

1 reference

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V(D)J recombination: RAG proteins, repair factors, and regulation

21 June 2018

1 reference

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Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

21 June 2018

1 reference

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Assembly of the RAG1/RAG2 synaptic complex

21 June 2018

1 reference

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Functional organization of single and paired V(D)J cleavage complexes

21 June 2018

1 reference

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Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set

21 June 2018

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The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire

21 June 2018

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Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy

21 June 2018

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

21 June 2018

1 reference

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Spectroscopic methods for analysis of protein secondary structure

21 June 2018

1 reference

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Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

21 June 2018

1 reference

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Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

21 June 2018

1 reference

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Integrating DNA: transposases and retroviral integrases

21 June 2018

1 reference

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A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.

21 June 2018

1 reference

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A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions.

21 June 2018

1 reference

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Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

21 June 2018

1 reference

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Expression and V(D)J recombination activity of mutated RAG-1 proteins

21 June 2018

1 reference

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Analysis of regions of RAG-2 important for V(D)J recombination

21 June 2018

1 reference

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Definition of a core region of RAG-2 that is functional in V(D)J recombination

21 June 2018

1 reference

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Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

21 June 2018

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The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

21 June 2018

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The V(D)J recombination activating gene, RAG-1.

21 June 2018

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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

21 June 2018

1 reference

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Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

21 June 2018

1 reference

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Characterization of the self association of Avian sarcoma virus integrase by analytical ultracentrifugation

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152797

Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12655019

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A zinc-binding domain involved in the dimerization of RAG1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12655019

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKG281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655019%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655019%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

12655019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12655019%20AND%20SRC:MED&resulttype=core&format=json