Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data (Q31144148)

12 August 2017

1 reference

title

Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data (English)

1 reference

12 August 2017

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Rebecca J Brown

1

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PMCID

3417290

12 August 2017

Kristina I Rother

series ordinal

2

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12 August 2017

24 January 2008

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12 August 2017

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12 August 2017

9

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12 August 2017

3 Pt 2

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12 August 2017

14-22

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Diabetes Treatment — Bridging the Divide

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

TLR4 links innate immunity and fatty acid-induced insulin resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

The biology of incretin hormones

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of glucokinase in pancreatic beta-cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

A comprehensive review of interventions in the NOD mouse and implications for translation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Intensive insulin therapy protects the endothelium of critically ill patients

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Functional rest through intensive treatment with insulin and potassium channel openers preserves residual beta-cell function and mass in acutely diabetic BB rats.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Beta-cell rest: a strategy for the prevention of autoimmune diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Regulation of glutamic acid decarboxylase diabetes autoantigen expression in highly purified isolated islets from Macaca nemestrina

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Diazoxide and the treatment of hypoglycemia: an historical review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Insulin treatment improves glucose-induced insulin release in rats with NIDDM induced by streptozocin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Improved beta-cell function after intensive insulin treatment in severe non-insulin-dependent diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific, BB rat monoclonal autoantibody IC2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Diabetes prevention in BB rats by inhibition of endogenous insulin secretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Sustained insulin-induced remissions of juvenile diabetes by means of an external artificial pancreas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Improvement in insulin secretion in diabetes after diazoxide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Insulin granule dynamics in pancreatic beta cells

28 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Subtotal pancreatectomy for hypoglycemia due to congenital hyperinsulinism: long-term follow-up of neurodevelopmental and pancreatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Peptide-binding G protein-coupled receptors: new opportunities for drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Octreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

K(ATP) channels and pancreatic islet blood flow in anesthetized rats: increased blood flow induced by potassium channel openers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective po

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Improved beta-cell survival and reduced insulitis in a type 1 diabetic rat model after treatment with a beta-cell-selective K(ATP) channel opener.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Effects of insulin in relatives of patients with type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Long-term prophylactic insulin treatment can prevent spontaneous diabetes and thyroiditis development in the diabetes-prone bio-breeding rat, while short-term treatment is ineffective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Short-term insulin therapy in adolescents with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Short-term intensive insulin therapy in newly diagnosed type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Induction of beta-cell rest in type 1 diabetes. Studies on the effects of octreotide and diazoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Sulfonylurea induced beta-cell apoptosis in cultured human islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Induction of Long-Term Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients by Transient Intensive Insulin Treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-5448.2007.00272.X

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Effects of timely insulin treatment on protection of beta cells in a rat model of type 2 diabetes mellitus

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Improved beta cell function after short-term treatment with diazoxide in obese subjects with type 2 diabetes.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

Beta cell rest and recovery--does it bring patients with latent autoimmune diabetes in adults to euglycemia?

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417290

A randomized trial of a somatostatin analog for preserving beta cell function in children with insulin dependent diabetes mellitus

25 November 2018

1 reference

12 December 2020

Diazoxide causes recovery of beta-cell glucose responsiveness in 90% pancreatectomized diabetic rats

1 reference

12 December 2020

Hyperglycemia and hyperinsulinemia have additive effects on activation and proliferation of pancreatic stellate cells: possible explanation of islet-specific fibrosis in type 2 diabetes mellitus

1 reference

12 December 2020

Insulin decreases intracellular oxidative stress in patients with type 2 diabetes mellitus

1 reference

12 December 2020

K(ATP) channel openers protect rat islets against the toxic effect of streptozotocin

1 reference

12 December 2020

Effect of a new long-acting somatostatin analogue (SMS 201-995) on glycemic and hormonal profiles in insulin-treated type II diabetic patients

1 reference

12 December 2020

Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice

1 reference

12 December 2020

Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control and Complications Trial Research Group

1 reference

12 December 2020

Metabolic diapause in pancreatic beta-cells expressing a gain-of-function mutant of the forkhead protein Foxo1

1 reference

12 December 2020

Specific inhibition of rat pancreatic insulin or glucagon release by receptor-selective somatostatin analogs

1 reference

12 December 2020

Glucose regulation of the autoantigen GAD65 in human pancreatic islets

1 reference

12 December 2020

Inhibition of human pancreatic islet insulin release by receptor-selective somatostatin analogs directed to somatostatin receptor subtype 5

1 reference

12 December 2020

10.1111/J.1399-5448.2007.00272.X

Identifiers

DOI

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

3417290