Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels (Q31384854)

1 July 2017

Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels (English)

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1 July 2017

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Tudor G

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1 July 2017

Aguilera A

2

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1 July 2017

Halverson DO

3

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1 July 2017

Laing ND

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1 July 2017

Sausville EA

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1 July 2017

1 June 2000

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Cell Death & Differentiation

1 July 2017

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1 July 2017

7

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1 July 2017

6

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1 July 2017

574-586

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Double identity for proteins of the Bcl-2 family

1 July 2017

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Induction of apoptosis by the Bcl-2 homologue Bak

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bcl-2 phosphorylation required for anti-apoptosis function

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Inactivation of Bcl-2 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

21 January 2018

Caspases: enemies within

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Protease activation during apoptosis: death by a thousand cuts?

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Alkylation of DNA with aziridine produced during the hydrolysis of N,N',N''-triethylenethiophosphoramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Promotion of microtubule assembly in vitro by taxol

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Cell kill kinetics and cell cycle effects of taxol on human and hamster ovarian cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Basic fibroblast growth factor downregulates Bcl-2 and promotes apoptosis in MCF-7 human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bak can accelerate chemotherapy-induced cell death independently of its heterodimerization with Bcl-XL and Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

7 January 2021

Checkpoints of dueling dimers foil death wishes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

7 January 2021

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

7 January 2021

Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

7 January 2021

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

7 January 2021

Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400688

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400688

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Dimensions Publication ID

1 July 2017

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