Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. (Q31506532)

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1 November 2019

title

Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction (English)

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1 November 2019

main subject

Cell–cell interaction

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4

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1 November 2019

author name string

Tarui T

series ordinal

1

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1 November 2019

Mazar AP

series ordinal

2

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1 November 2019

Cines DB

series ordinal

3

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1 November 2019

language of work or name

English

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publication date

26 October 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11053440%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 November 2019

published in

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volume

276

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issue

6

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1 November 2019

page(s)

3983-3990

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The urokinase plasminogen activator system in cancer: implications for tumor angiogenesis and metastasis

1 November 2019

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Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

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A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

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Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction

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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

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Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction

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Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

21 January 2018

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The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells.

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Regulation of integrin function by the urokinase receptor

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The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

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A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

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The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

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Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

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Molecular interactions in cell adhesion complexes

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The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin

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Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits

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Requirement for VLA-4 and VLA-5 integrins in lymphoma cells binding to and migration beneath stromal cells in culture

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Differential regulation of airway epithelial integrins by growth factors

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A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex

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Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

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Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of fibronectin receptor

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Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3

21 January 2018

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RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction

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Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

21 January 2018

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Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and -independent signaling modules.

21 January 2018

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The properdin-like type I repeats of human thrombospondin contain a cell attachment site

21 January 2018

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21 January 2018

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A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques

21 January 2018

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21 January 2018

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21 January 2018

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Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)

21 January 2018

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A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

21 January 2018

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21 January 2018

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21 January 2018

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Soluble urokinase plasminogen activator receptor in plasma of patients with inflammatory rheumatic disorders: increased concentrations in rheumatoid arthritis

21 January 2018

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21 January 2018

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21 January 2018

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Urokinase receptor (uPAR, CD87) is a platelet receptor important for kinetics and TNF-induced endothelial adhesion in mice

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21 January 2018

Identifiers

DOI

10.1074/JBC.M008220200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11053440%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference