The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton. (Q31673052)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11113155%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton (English)

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2 November 2019

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2 November 2019

Martin A Schwartz

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2 November 2019

author name string

A Obergfell

1

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2 November 2019

B A Judd

2

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2 November 2019

G A Koretzky

5

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2 November 2019

S J Shattil

6

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2 November 2019

language of work or name

English

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publication date

11 December 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11113155%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 November 2019

published in

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2 November 2019

volume

276

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2 November 2019

issue

8

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2 November 2019

page(s)

5916-5923

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2 November 2019

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https://api.crossref.org/works/10.1074%2FJBC.M010639200

Integrin cytoplasmic interactions and bidirectional transmembrane signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M010639200

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M010639200

Signaling through scaffold, anchoring, and adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Integrin cytoplasmic domains mediate inside-out signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Low molecular weight, non-peptide fibrinogen receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Are changes in integrin affinity and conformation overemphasized?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Mechanisms of actin rearrangements mediating platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Actin machinery: pushing the envelope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Focal adhesions - the cytoskeletal connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

Spatial Control of Actin Filament Assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

VASP dynamics during lamellipodia protrusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010639200

21 January 2018

Identifiers

DOI

10.1074/JBC.M010639200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11113155%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference