Prion and prejudice: normal protein and the synapse (Q31874508)

4 July 2017

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title

Prion and prejudice: normal protein and the synapse (English)

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4 July 2017

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Brown DR

1

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4 July 2017

publication date

1 February 2001

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4 July 2017

published in

Trends in Neurosciences

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4 July 2017

volume

24

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4 July 2017

issue

2

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4 July 2017

page(s)

85-90

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Novel proteinaceous infectious particles cause scrapie

4 July 2017

cites work

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Molecular biology of prion diseases

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Prion protein expression in muscle cells and toxicity of a prion protein fragment

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7 January 2021

Microglial expression of the prion protein

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Activation effects of a prion protein fragment [PrP-(106-126)] on human leucocytes

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Cellular prion protein localization in rodent and primate brain

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7 January 2021

Ultrastructural localization of prion proteins: physiological and pathological implications

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7 January 2021

Evidence of presynaptic location and function of the prion protein

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7 January 2021

Synaptic prion protein immuno-reactivity in the rodent cerebellum.

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Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform

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Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

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cDNA cloning of turtle prion protein

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

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129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

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7 January 2021

Altered circadian activity rhythms and sleep in mice devoid of prion protein

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7 January 2021

Prion protein is necessary for normal synaptic function

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Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents.

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Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

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7 January 2021

B lymphocytes and neuroinvasion

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Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity

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Prions prevent neuronal cell-line death.

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Effects of copper on survival of prion protein knockout neurons and glia.

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Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity

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Astrocytic glutamate uptake and prion protein expression

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7 January 2021

Evidence for oxidative stress in experimental prion disease

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7 January 2021

Increased Sensitivity to Seizures in Mice Lacking Cellular Prion Protein

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7 January 2021

Mossy fibre reorganization in the hippocampus of prion protein null mice

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7 January 2021

NMR structure of the mouse prion protein domain PrP(121-231)

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7 January 2021

Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.

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7 January 2021

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

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7 January 2021

Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides

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High-affinity uptake of 67Cu into a veratridine-releasable pool in brain tissue

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Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase

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7 January 2021

Effects of divalent metal ions on the uptake of glutamate and GABA from synaptosomal fractions

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7 January 2021

Copper modulation of NMDA responses in mouse and rat cultured hippocampal neurons

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7 January 2021

Prion protein expression aids cellular uptake and veratridine-induced release of copper

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7 January 2021

Copper stimulates endocytosis of the prion protein

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7 January 2021

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

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Redox-regulation of intrinsic prion expression in multicellular prostate tumor spheroids

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7 January 2021

Effects of oxidative stress on prion protein expression in PC12 cells

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7 January 2021

Normal prion protein has an activity like that of superoxide dismutase.

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7 January 2021

Differential contribution of superoxide dismutase activity by prion protein in vivo

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7 January 2021

Consequences of manganese replacement of copper for prion protein function and proteinase resistance

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7 January 2021

The octapeptide repeat region of prion protein binds Cu(II) in the redox-inactive state

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7 January 2021

Selective oxidation of methionine residues in prion proteins

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7 January 2021

Dendritic and synaptic alterations of hippocampal pyramidal neurones in scrapie-infected mice

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7 January 2021

Mice devoid of PrP are resistant to scrapie

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7 January 2021

PrPSc-like prion protein peptide inhibits the function of cellular prion protein

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7 January 2021

Molecular properties of complexes formed between the prion protein and synthetic peptides.

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7 January 2021

Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

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7 January 2021

10.1016/S0166-2236(00)01689-1

Identifiers

DOI

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4 July 2017

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