Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene (Q31881413)

4 July 2017

title

Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene (English)

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4 July 2017

C J Saranko

1

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4 July 2017

K G Meyer

2

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4 July 2017

L J Pluta

3

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4 July 2017

R F Henderson

4

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4 July 2017

L Recio

5

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4 July 2017

language of work or name

English

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publication date

1 January 2001

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4 July 2017

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4 July 2017

volume

473

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4 July 2017

issue

1

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4 July 2017

page(s)

37-49

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The industrial production and use of 1,3-butadiene

4 July 2017

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Characterization of hprt mutations following 1,2-epoxy-3-butene exposure of human TK6 cells

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Molecular analysis of lacI mutants from transgenic fibroblasts exposed to 1,2-epoxybutene

7 January 2021

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Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts

7 January 2021

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Analysis of hprt mutations occurring in human TK6 lymphoblastoid cells following exposure to 1,2,3,4-diepoxybutane

7 January 2021

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Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.

7 January 2021

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Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes

7 January 2021

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Toxicology and epidemiology of 1,3-butadiene

7 January 2021

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Determination of mutagenicity in tissues of transgenic mice following exposure to 1,3-butadiene and N-ethyl-N-nitrosourea

7 January 2021

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Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene.

7 January 2021

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The in vivo mutagenicity and mutational spectrum at the lacI transgene recovered from the spleens of B6C3F1 lacI transgenic mice following a 4-week inhalation exposure to 1,3-butadiene

7 January 2021

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Increased frequency of mutations at A:T base pairs in the bone marrow of B6C3F1 lacl transgenic mice exposed to 1, 3‐butadiene

7 January 2021

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The butadiene metabolite, 1,2:3,4-diepoxybutane, induces micronuclei but is only weakly mutagenic at lacI in the Big Blue Rat2 lacI transgenic cell line

7 January 2021

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In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data

7 January 2021

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Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.

7 January 2021

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Transgenic lambda/lacI mutagenicity assay: statistical determination of sample size

7 January 2021

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7 January 2021

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Mutagenicity of the racemic mixtures of butadiene monoepoxide and butadiene diepoxide at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats

7 January 2021

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Spontaneous mutation in lacI transgenic mice: a comparison of tissues.

7 January 2021

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Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Diepoxybutane cross-links DNA at 5'-GNC sequences

7 January 2021

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7 January 2021

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Localization of metabolic activation and deactivation systems in the lung: significance to the pulmonary toxicity of xenobiotics

7 January 2021

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Localization, distribution, and induction of xenobiotic-metabolizing enzymes and aryl hydrocarbon hydroxylase activity within lung

7 January 2021

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Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung

7 January 2021

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10.1016/S0027-5107(00)00122-6

7 January 2021

Identifiers

DOI

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4 July 2017

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