The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status (Q31881430)

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English	The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 July 2017

The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status (English)

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Europe PubMed Central

PubMed publication ID

4 July 2017

1 reference

based on heuristic

inferred from title

folate deficiency

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based on heuristic

inferred from title

author name string

Branda RF

1

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Europe PubMed Central

PubMed publication ID

4 July 2017

O'Neill JP

2

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Europe PubMed Central

PubMed publication ID

4 July 2017

Brooks EM

3

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Trombley LM

4

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Europe PubMed Central

PubMed publication ID

4 July 2017

Nicklas JA

5

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Europe PubMed Central

PubMed publication ID

4 July 2017

language of work or name

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publication date

1 January 2001

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Europe PubMed Central

PubMed publication ID

4 July 2017

Mutation Research

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Europe PubMed Central

PubMed publication ID

4 July 2017

473

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Europe PubMed Central

PubMed publication ID

4 July 2017

1

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Europe PubMed Central

PubMed publication ID

4 July 2017

51-71

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Europe PubMed Central

PubMed publication ID

4 July 2017

Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes

1 reference

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7 January 2021

Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells.

1 reference

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Nutritional folate deficiency augments the in vivo mutagenic and lymphocytotoxic activities of alkylating agents

1 reference

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7 January 2021

Factors influencing mutation at the hprt locus in T-lymphocytes: studies in normal women and women with benign and malignant breast masses

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Mutant frequency at the hprt locus in human lymphocytes in a case-control study of lung cancer

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Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats

1 reference

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7 January 2021

Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene

1 reference

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7 January 2021

Uracil misincorporation in human DNA detected using single cell gel electrophoresis.

1 reference

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7 January 2021

Misincorporation of uracil into the DNA of folate- and B12-deficient HL60 cells

1 reference

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7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

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7 January 2021

Structures and functions of DNA glycosylases

1 reference

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7 January 2021

Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation.

1 reference

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7 January 2021

Folate depletion impairs DNA excision repair in the colon of the rat.

1 reference

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7 January 2021

The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents

1 reference

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7 January 2021

Different cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid cell lines derived from a single donor

1 reference

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7 January 2021

Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells

1 reference

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7 January 2021

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

1 reference

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7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

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7 January 2021

Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status

1 reference

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7 January 2021

Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

1 reference

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7 January 2021

Evidence of the involvement of p53 in gamma-radiation-induced DNA repair in human lymphoblasts

1 reference

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7 January 2021

Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery

1 reference

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7 January 2021

p53 Expression in normal versus transformed mammalian cells

1 reference

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7 January 2021

Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing

1 reference

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7 January 2021

Cloning and characterization of Chinese hamster p53 cDNA.

1 reference

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7 January 2021

Amplification and direct nucleotide sequencing of cDNA from the lysate of low numbers of diploid human cells

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7 January 2021

Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families

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7 January 2021

Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum

1 reference

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7 January 2021

An evaluation of the CHO/HGPRT mutation assay involving suspension cultures and soft agar cloning: results for 33 chemicals

1 reference

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7 January 2021

Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: possible role of apoptosis

1 reference

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7 January 2021

Selective elimination of human lymphoid cells with unstable chromosome aberrations by p53-dependent apoptosis

1 reference

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7 January 2021

Folate deficiency induces a cell cycle-specific apoptosis in HepG2 cells

1 reference

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7 January 2021

Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation

1 reference

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7 January 2021

p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900138-X

7 January 2021

Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2

1 reference

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7 January 2021

Influence of p53 tumor suppressor protein on bias of DNA repair and apoptotic response in human cells

1 reference

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7 January 2021

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

1 reference

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7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

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7 January 2021

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

1 reference

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7 January 2021

International Commission for Protection Against Environmental Mutagens and Carcinogens. The subtlety of alkylating agents in reactions with biological macromolecules

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7 January 2021

Release of 7-methylguanine residues from alkylated DNA by extracts of Micrococcus luteus and Escherichia coli

1 reference

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7 January 2021

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines

1 reference

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7 January 2021

Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts

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7 January 2021

Methyl methanesulfonate-induced hprt mutation spectra in the Chinese hamster cell line CHO9 and its xrcc1-deficient derivative EM-C11.

1 reference

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7 January 2021

Human lymphoblastoid lines from lymph node and spleen

1 reference

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Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: Possibility for a rapid human cell mutation assay

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7 January 2021

Evidence for indirect involvement of thymidine kinase in excision repair processes in mouse cell lines

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Sensitivity to cell killing and the induction of cytogenetic damage following gamma irradiation in wild-type and thymidine kinase-deficient Friend mouse erythroleukaemia cells

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Thymidine kinase deficient cells with decreased TTP pools are hypersensitive to DNA alkylating agents

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Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.

1 reference

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The role of blood platelets in nucleoside metabolism: regulation of megakaryocyte development and platelet production

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Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues

1 reference

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Automated DNA sequencing of the human HPRT locus

1 reference

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7 January 2021

Increased methotrexate-induced DNA strand breaks and cytotoxicity following mutational loss of thymidine kinase

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7 January 2021

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10.1016/S0027-5107(00)00138-X

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Europe PubMed Central

PubMed publication ID

4 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

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