Comparative effects of metal chelating agents on the neuronal cytotoxicity induced by copper (Cu+2), iron (Fe+3) and zinc in the hippocampus (Q31923540)

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English	Comparative effects of metal chelating agents on the neuronal cytotoxicity induced by copper (Cu+2), iron (Fe+3) and zinc in the hippocampus	scientific article

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scholarly article

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Europe PubMed Central

5 July 2017

Comparative effects of metal chelating agents on the neuronal cytotoxicity induced by copper (Cu+2), iron (Fe+3) and zinc in the hippocampus (English)

1 reference

Europe PubMed Central

5 July 2017

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author name string

C Armstrong

1

1 reference

Europe PubMed Central

5 July 2017

W Leong

2

1 reference

Europe PubMed Central

5 July 2017

G J Lees

3

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Europe PubMed Central

5 July 2017

language of work or name

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publication date

1 February 2001

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Europe PubMed Central

5 July 2017

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Europe PubMed Central

5 July 2017

892

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Europe PubMed Central

5 July 2017

1

1 reference

Europe PubMed Central

5 July 2017

51-62

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Europe PubMed Central

5 July 2017

Depletion of intracellular zinc induces protein synthesis-dependent neuronal apoptosis in mouse cortical culture.

1 reference

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Diethyldithiocarbamate, copper and neurological disorders

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Copper toxicity in cultured human skeletal muscle cells: the involvement of Na+/K(+)-ATPase and the Na+/Ca(2+)-exchanger

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Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy

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The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.

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Role of iron and iron chelation in dopaminergic-induced neurodegeneration: implication for Parkinson's disease

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Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats

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Deferoxamine (desferrioxamine). New toxicities for an old drug

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Treatment of Wilson's disease with ammonium tetrathiomolybdate. I. Initial therapy in 17 neurologically affected patients.

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7 January 2021

Treatment of Wilson disease with ammonium tetrathiomolybdate. II. Initial therapy in 33 neurologically affected patients and follow-up with zinc therapy

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7 January 2021

Worsening of neurologic syndrome in patients with Wilson's disease with initial penicillamine therapy

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Zn2+ inhibits alpha-ketoglutarate-stimulated mitochondrial respiration and the isolated alpha-ketoglutarate dehydrogenase complex

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Zinc neurotoxicity in cortical cell culture

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Seizures and neuronal damage in mice lacking vesicular zinc.

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A histochemical study of iron, transferrin, and ferritin in Alzheimer's diseased brains.

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Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

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Prevention of zinc neurotoxicity in vivo by N,N,N',N'-tetrakis (2-pyridylmethyl) ethylene-diamine (TPEN)

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Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya.

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Diverse effects of metal chelating agents on the neuronal cytotoxicity of zinc in the hippocampus.

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The effects of disulfiram on the hippocampus and cerebellum of the rat brain: a study on oxidative stress

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Wilson's disease and epilepsy

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Seizures in rats associated with divalent cation inhibition of NA + -K + -ATP'ase.

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Desmethyl tirilazad improves neurologic function after hypoxic ischemic brain injury in piglets.

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Translocation of zinc may contribute to seizure-induced death of neurons

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Aberrant copper chemistry as a major mediator of oxidative stress in a human cellular model of amyotrophic lateral sclerosis

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The potential role of iron chelators in the treatment of Parkinson's disease and related neurological disorders

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Oxygen radicals as key mediators in neurological disease: fact or fiction?

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Metal (molybdenum, copper) accumulation and retention in brain, pituitary and other organs of ammonium tetrathiomolybdate-treated sheep.

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7 January 2021

Endogenous mechanisms of neuroprotection: role of zinc, copper, and carnosine

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Risks of parenteral deferoxamine for acute iron poisoning

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The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

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The selective inhibition of hippocampal glutamic acid decarboxylase in zinc-induced epileptic seizures.

1 reference

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The role of proteolysis in T cell apoptosis triggered by chelation of intracellular Zn2+

1 reference

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The effect of ligands on the uptake of iron by cells in culture

1 reference

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Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.

1 reference

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Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals.

1 reference

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Hydrogen peroxide-mediated degradation of protein: different oxidation modes of copper- and iron-dependent hydroxyl radicals on the degradation of albumin

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Metabolism of administered triethylene tetramine dihydrochloride in humans

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The role of zinc in selective neuronal death after transient global cerebral ischemia

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Neurotoxic effects of copper: Inhibition of glycolysis and glycolytic enzymes

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Excessive iron accumulation in the brain: a possible potential risk of neurodegeneration in Parkinson's disease.

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Iron bound to the lipophilic iron chelator, 8-hydroxyquinoline, causes DNA strand breakage in cultured lung cells.

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Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin.

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Effects of anaesthetics, anticonvulsants and glutamate antagonists on kainic acid-induced local and distal neuronal loss

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The neurotoxicity of zinc in the rat hippocampus.

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Brain lesions induced by specific and non-specific inhibitors of sodium-potassium ATPase

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Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions

1 reference

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Altered systemic iron metabolism in Parkinson's disease.

1 reference

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Copper, iron and zinc in Alzheimer's disease senile plaques.

1 reference

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Failure of iron chelators to protect against cerebral infarction in hypoxia-ischemia.

1 reference

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Intramuscular desferrioxamine in patients with Alzheimer's disease

1 reference

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Reversibility of scrapie inactivation is enhanced by copper.

1 reference

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Proconvulsant action of diethyldithiocarbamate in stimulation of the perforant path.

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Diethyldithiocarbamate and dithizone augment the toxicity of kainic acid

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Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: a putative mechanism of degeneration

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Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide

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The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

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Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice

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Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes

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Comparative mechanism and toxicity of tetra- and dithiomolybdates in the removal of copper

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Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats.

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Involvement of zinc in intracellular oxidant/antioxidant balance.

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Features of seizures and behavioral changes induced by intrahippocampal injection of zinc sulfate in the rabbit: a new experimental model of epilepsy.

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Hippocampal epileptogenesis produced by electrolytic iron deposition in the rat dentate gyrus

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The toxic effects of desferrioxamine

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Prions are copper-binding proteins.

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Generation of reactive oxygen species by the redox cycling of nitroprusside

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Distribution of iron in different brain regions and subcellular compartments in Parkinson's disease

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H2O2-driven reduction of the Fe3+-quin2 chelate and the subsequent formation of oxidizing species

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Alzheimer's precursor protein and the use of bathocuproine for determining reduction of copper(II)

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Iron induces degeneration of nigrostriatal neurons

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Measurement of intracellular free zinc in living cortical neurons: routes of entry.

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Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production

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Zinc release from Xenopus transcription factor IIIA induced by chemical modifications.

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Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis

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Selective lesions by manganese and extensive damage by iron after injection into rat striatum or hippocampus

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Use of allopurinol and deferoxamine in cellular protection during ischemia

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The effect of subcutaneous tetrathiomolybdate administration on copper and iron metabolism, including their regional redistribution in the brain, in the Long-Evans Cinnamon rat, a bona fide animal model for Wilson's disease.

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Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains

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Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat.

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Iron-chelating agents in non-iron overload conditions

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Strain-specific prion-protein conformation determined by metal ions

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Management of penicillamine nephropathy in Wilson's disease: a new chelating agent

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Pathophysiological mechanisms of brain damage from status epilepticus

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AMPA receptor activation potentiates zinc neurotoxicity

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The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures

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Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

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Epileptiform activity initiated by pial iontophoresis of ferrous and ferric chloride on rat cerebral cortex

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Chronic Focal Epileptiform Discharges Induced by Injection of Iron Into Rat and Cat Cortex

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Inhibition of the DNA-binding activity of NF-kappa B by gold compounds in vitro

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Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Sp1.

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7 January 2021

Zinc transfer from transcription factor IIIA fingers to thionein clusters

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Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration.

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7 January 2021

Increased brain uptake of copper and zinc in mice caused by diethyldithiocarbamate

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7 January 2021

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10.1016/S0006-8993(00)03195-4

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Europe PubMed Central

5 July 2017

1 reference

Europe PubMed Central

5 July 2017

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