Roles of amino acids 161 to 179 in the PSE-4 omega loop in substrate specificity and in resistance to ceftazidime (Q32012271)

5 July 2017

Roles of amino acids 161 to 179 in the PSE-4 omega loop in substrate specificity and in resistance to ceftazidime (English)

1 reference

5 July 2017

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Therrien C

1

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5 July 2017

Sanschagrin F

series ordinal

2

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5 July 2017

Palzkill T

series ordinal

3

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5 July 2017

Levesque RC

series ordinal

4

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5 July 2017

language of work or name

English

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publication date

1 October 1998

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5 July 2017

8

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Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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5 July 2017

42

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5 July 2017

2576-2583

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5 July 2017

10

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Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases

5 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Cephalosporin substrate specificity determinants of TEM-1 beta-lactamase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

A point mutation leads to altered product specificity in beta-lactamase catalysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Amino acid sequence determinants of beta-lactamase structure and activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Systematic mutagenesis of the active site omega loop of TEM-1 beta-lactamase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

A catalytically-impaired class A beta-lactamase: 2 A crystal structure and kinetics of the Bacillus licheniformis E166A mutant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Characterization of TEM-1 beta-lactamase mutants from positions 238 to 241 with increased catalytic efficiency for ceftazidime.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Evolution of antibiotic resistance: several different amino acid substitutions in an active site loop alter the substrate profile of beta-lactamase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Site-directed mutagenesis of beta-lactamase I: role of Glu-166.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

TEM- and SHV-derived extended-spectrum beta-lactamases: relationship between selection, structure and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

A functional classification scheme for beta-lactamases and its correlation with molecular structure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Effects of Asp-179 mutations in TEMpUC19 beta-lactamase on susceptibility to beta-lactams

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

The release of enzymes from Escherichia coli by osmotic shock and during the formation of spheroplasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Kanamycin-resistant vectors that are analogues of plasmids pUC8, pUC9, pEMBL8 and pEMBL9.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

A standard numbering scheme for the class A beta-lactamases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Site-directed mutagenesis of beta-lactamase I. Single and double mutants of Glu-166 and Lys-73.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Structural basis for the inactivation of the P54 mutant of beta-lactamase from Staphylococcus aureus PC1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Identification of amino acid substitutions that alter the substrate specificity of TEM-1 beta-lactamase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Phylogeny of LCR-1 and OXA-5 with class A and class D beta-lactamases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105900

Insertion mutagenesis as a tool in the modification of protein function. Extended substrate specificity conferred by pentapeptide insertions in the omega-loop of TEM-1 beta-lactamase

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9756758

12 December 2020

inferred from PubMed ID database lookup

The structural stability of a protein is an important determinant of its proteolytic susceptibility in Escherichia coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9756758

12 December 2020

inferred from PubMed ID database lookup

Site-directed mutants, at position 166, of RTEM-1 beta-lactamase that form a stable acyl-enzyme intermediate with penicillin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9756758

12 December 2020

inferred from PubMed ID database lookup

Identifiers

PMCID

105900

1 reference

5 July 2017

1 reference