Preclinical evaluation of a phosphorothioate oligonucleotide in the retina of rhesus monkey (Q32063152)

6 July 2017

title

Preclinical evaluation of a phosphorothioate oligonucleotide in the retina of rhesus monkey (English)

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6 July 2017

Wei-Yong Shen

1

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6 July 2017

Kerryn L Garrett

2

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6 July 2017

Chang-Guan Wang

3

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6 July 2017

Kun Zhang

4

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6 July 2017

Zhi-Zhong Ma

5

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6 July 2017

Ian J Constable

6

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6 July 2017

P Elizabeth Rakoczy

7

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6 July 2017

publication date

1 February 2002

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6 July 2017

number of pages

16

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inferred from page(s)

published in

Laboratory Investigation

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6 July 2017

volume

82

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6 July 2017

issue

2

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6 July 2017

page(s)

167-182

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Retinal and choroidal neovascularization

6 July 2017

cites work

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ICGA-guided laser photocoagulation of occult choroidal neovascularization in age-related macular degeneration. Indocyanine green angiography

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Evaluation of retinal toxicity and efficacy of anti-cytomegalovirus and anti-herpes simplex virus antiviral phosphorothioate oligonucleotides ISIS 2922 and ISIS 4015.

21 January 2018

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In vivo use of oligonucleotides to inhibit choroidal neovascularisation in the eye.

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Modification of phosphorothioate oligonucleotides yields potent analogs with minimal toxicity for antisense experiments in the CNS.

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Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA

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Expression of vascular endothelial growth factor in experimental choroidal neovascularization

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Phosphorothioate oligonucleotides induction into experimental choroidal neovascularization by HVJ-liposome system

21 January 2018

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Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization

21 January 2018

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Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization

21 January 2018

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Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy

21 January 2018

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Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium

21 January 2018

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Inhibition of diclofenac formulated in hyaluronan on angiogenesis in vitro and its intraocular tolerance in the rabbit eye.

21 January 2018

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Dynamics of phosphorothioate oligonucleotides in normal and laser photocoagulated retina

21 January 2018

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Expression of cell adhesion molecules and vascular endothelial growth factor in experimental choroidal neovascularisation in the rat.

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Treatment options In subfoveal choroidal neovascularization secondary to age-related macular degeneration

21 January 2018

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Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization

21 January 2018

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Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

21 January 2018

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Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

21 January 2018

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Reversible bull's-eye maculopathy associated with intravitreal fomivirsen therapy for cytomegalovirus retinitis

21 January 2018

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Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells

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Age-related macular degeneration

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7 January 2021

In vivo delivery of phosphorothioate oligonucleotides into murine retina

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7 January 2021

Targeted delivery of an antisense oligonucleotide in the retina: uptake, distribution, stability, and effect

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7 January 2021

Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: ii. quality of life outcomes submacular surgery trials pilot study rep

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7 January 2021

10.1038/LABINVEST.3780409

Identifiers

DOI

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Dimensions Publication ID

6 July 2017

1036110570

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