How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology (Q32138928)

6 July 2017

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title

How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology (English)

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6 July 2017

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M P Murphy

1

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PubMed ID

11239480

6 July 2017

language of work or name

English

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publication date

1 March 2001

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Biochimica et Biophysica Acta

6 July 2017

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6 July 2017

1504

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6 July 2017

1

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6 July 2017

1-11

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Regulation of cellular energy metabolism

6 July 2017

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Control of electron flux through the respiratory chain in mitochondria and cells

7 January 2021

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Control of respiration and ATP synthesis in mammalian mitochondria and cells

7 January 2021

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Mitochondrial diseases in man and mouse

7 January 2021

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Control of oxidative phosphorylation in mitochondria, cells and tissues

7 January 2021

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Top-down elasticity analysis and its application to energy metabolism in isolated mitochondria and intact cells

7 January 2021

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Mitochondria: a historical review

7 January 2021

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Non-equilibrium thermodynamics of energy conversion in bioenergetics

7 January 2021

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Molecular Democracy: Who Shares the Controls?

7 January 2021

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A Linear Steady-State Treatment of Enzymatic Chains. General Properties, Control and Effector Strength

7 January 2021

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Modern theories of metabolic control and their applications

7 January 2021

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Metabolic control analysis: a survey of its theoretical and experimental development

7 January 2021

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Control of mitochondrial respiration.

7 January 2021

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Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration.

7 January 2021

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A 'top-down' approach to the determination of control coefficients in metabolic control theory.

7 January 2021

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Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory

7 January 2021

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Control of respiration and oxidative phosphorylation in isolated rat liver cells

7 January 2021

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Control of oxidative phosphorylation, gluconeogenesis, ureagenesis and ATP turnover in isolated perfused rat liver analyzed by top-down metabolic control analysis

7 January 2021

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Top down metabolic control analysis.

7 January 2021

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Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes

7 January 2021

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Control of mitochondrial ATP synthesis in the heart

7 January 2021

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The allosteric ATP-inhibition of cytochrome c oxidase activity is reversibly switched on by cAMP-dependent phosphorylation

7 January 2021

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Nitric oxide and mitochondrial respiration

7 January 2021

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Nitric oxide synthase activity in mitochondria

7 January 2021

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3,5-Diiodothyronine binds to subunit Va of cytochrome-c oxidase and abolishes the allosteric inhibition of respiration by ATP.

7 January 2021

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Thyroid-hormone control of state-3 respiration in isolated rat liver mitochondria

7 January 2021

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Altered relationship between protonmotive force and respiration rate in non-phosphorylating liver mitochondria isolated from rats of different thyroid hormone status

7 January 2021

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Mitochondrial biogenesis in skeletal muscle in response to endurance exercises

7 January 2021

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Changes in the hepatic mitochondrial respiratory system in the transition from weaning to adulthood in rats

7 January 2021

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The uncoupling proteins, a review.

7 January 2021

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Taking enzyme kinetics out of control; putting control into regulation

7 January 2021

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Quantitative assessment of regulation in metabolic systems

7 January 2021

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Theoretical studies on the control of oxidative phosphorylation in muscle mitochondria: application to mitochondrial deficiencies

7 January 2021

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Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes

7 January 2021

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Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia?

7 January 2021

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Control analysis of energy metabolism in mitochondria.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2728%2800%2900234-6

Stimulation of the electron transport chain in mitochondria isolated from rats treated with mannoheptulose or glucagon

7 January 2021

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Effects of chronic ethanol feeding on rat liver mitochondrial energy metabolism

7 January 2021

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Chronic ethanol ingestion increases efficiency of oxidative phosphorylation in rat liver mitochondria.

7 January 2021

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The effect of chloroform on mitochondrial energy transduction

7 January 2021

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Interaction of butylated hydroxyanisole with mitochondrial oxidative phosphorylation

7 January 2021

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The free radical theory of aging matures

7 January 2021

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Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications

7 January 2021

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Mitochondrial genetics: a paradigm for aging and degenerative diseases?

7 January 2021

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Mitochondrial DNA sequence variation in human evolution and disease.

7 January 2021

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In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria

7 January 2021

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MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts

7 January 2021

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Bioenergetic consequences of accumulating the common 4977-bp mitochondrial DNA deletion

7 January 2021

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Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations.

7 January 2021

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Abnormal calcium homeostasis and mitochondrial polarization in a human encephalomyopathy

7 January 2021

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Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria

7 January 2021

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Human deafness dystonia syndrome is a mitochondrial disease

7 January 2021

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Mitochondrial function in neurodegeneration and ageing

7 January 2021

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Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

7 January 2021

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Brain Cytochrome Oxidase in Alzheimer's Disease

7 January 2021

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Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations

7 January 2021

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A hierarchy of ATP-consuming processes in mammalian cells

7 January 2021

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Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase

7 January 2021

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Threshold effect and tissue specificity. Implication for mitochondrial cytopathies

7 January 2021

1 reference

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Control of oxidative phosphorylation in rat muscle mitochondria: implications for mitochondrial myopathies.

7 January 2021

1 reference

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The control of electron flux through cytochrome oxidase

7 January 2021

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In vivo control of respiration by cytochrome c oxidase in wild-type and mitochondrial DNA mutation-carrying human cells

7 January 2021

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Drug delivery to mitochondria: the key to mitochondrial medicine

7 January 2021

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Selective targeting of bioactive compounds to mitochondria

7 January 2021

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A model for p53-induced apoptosis

7 January 2021

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Gene expression profile of aging and its retardation by caloric restriction

7 January 2021

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Determining and understanding the control of flux. An illustration in submitochondrial particles of how to validate schemes of metabolic control

7 January 2021

1 reference

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10.1016/S0005-2728(00)00234-6

7 January 2021

Identifiers

DOI

1 reference

6 July 2017

1 reference

PubMed ID

11239480