Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts (Q32160638)

6 July 2017

Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts (English)

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6 July 2017

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R Conejo

1

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PubMed ID

11241354

6 July 2017

M Lorenzo

series ordinal

2

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6 July 2017

1 April 2001

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Journal of Cellular Physiology

6 July 2017

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6 July 2017

187

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6 July 2017

1

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6 July 2017

96-108

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

6 July 2017

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Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IGF-II-induced proliferation and differentiation of L6A1 rat myoblasts

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Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases

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Plasticity of the differentiated state

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Effects of general receptor for phosphoinositides 1 on insulin and insulin-like growth factor I-induced cytoskeletal rearrangement, glucose transporter-4 translocation, and deoxyribonucleic acid synthesis

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The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways.

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Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

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Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

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Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells

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Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: dominant negative p85 expression blocks differentiation of L6E9 muscle cells

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The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activate

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IGF-I is a mitogen involved in differentiation-related gene expression in fetal rat brown adipocytes

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Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry

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Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways

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Insulin/IGF-I rescues immortalized brown adipocytes from apoptosis down-regulating Bcl-xS expression, in a PI 3-kinase- and map kinase-dependent manner

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Activated Ha-ras induces apoptosis by association with phosphorylated Bcl-2 in a mitogen-activated protein kinase-independent manner.

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts

21 January 2018

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Insulin-like growth factor-II is an autocrine survival factor for differentiating myoblasts

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The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

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Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts

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Insulin-like growth factor I and insulin induce adipogenic-related gene expression in fetal brown adipocyte primary cultures.

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Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase

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The molecular biology of apoptosis

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Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

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Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

21 January 2018

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Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

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A simple, rapid, and sensitive DNA assay procedure

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Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

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Evidence for a direct interaction between insulin receptor substrate-1 and Shc

21 January 2018

1 reference

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Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase

21 January 2018

1 reference

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Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migration

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PKB Inhibition Prevents the Stimulatory Effect of Insulin on Glucose Transport and Protein Translocation but Not the Antilipolytic Effect in Rat Adipocytes

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cAMP inhibits IGF-I-induced mitogenesis in fetal rat brown adipocytes: role of p21 ras

21 January 2018

1 reference

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Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes

21 January 2018

1 reference

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10.1002/1097-4652(2001)9999:9999<::AID-JCP1058>3.0.CO;2-V

21 January 2018

Identifiers

DOI

1 reference

6 July 2017

1 reference

PubMed ID

11241354