Gamma-butyrobetaine hydroxylase 1 (Q3266583)

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mammalian protein found in Homo sapiens

• BBOX1
• gamma-butyrobetaine dioxygenase
• Gamma-BBH
• Gamma-butyrobetaine,2-oxoglutarate dioxygenase
• gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
• butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
• Gamma-butyrobetaine hydroxylase

edit

Language	Label	Description	Also known as
English	Gamma-butyrobetaine hydroxylase 1	mammalian protein found in Homo sapiens	BBOX1 gamma-butyrobetaine dioxygenase Gamma-BBH Gamma-butyrobetaine,2-oxoglutarate dioxygenase gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 Gamma-butyrobetaine hydroxylase

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O75936

part of

Gamma-butyrobetaine hydroxylase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75936

GBBH-like, N-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75936

TauD/TfdA-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Gamma-butyrobetaine hydroxylase-like, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O75936

encoded by

BBOX1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O75936

molecular function

iron ion binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

oxidoreductase activity

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

zinc ion binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Crystal structure of human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IDA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IPI

dioxygenase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

metal ion binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

identical protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IPI

gamma-butyrobetaine dioxygenase activity

determination method

EXP

IDA

IEA

ISS

6 references

retrieved

26 September 2017

stated in

Molecular cloning and characterization of the cDNA encoding the rat liver gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

ISS

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

26 September 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

26 September 2017

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

26 September 2017

stated in

Crystal structure of human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

26 September 2017

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

EXP

gamma-butyrobetaine dioxygenase activity

determination method

EXP

IBA

IDA

IEA

ISS

7 references

retrieved

1 January 2018

stated in

Molecular cloning and characterization of the cDNA encoding the rat liver gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

ISS

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

1 January 2018

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

1 January 2018

stated in

Crystal structure of human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IBA

retrieved

1 January 2018

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

EXP

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IBA

gamma-butyrobetaine dioxygenase activity

determination method

IBA

IDA

IEA

ISS

6 references

retrieved

8 April 2019

stated in

Molecular cloning and characterization of the cDNA encoding the rat liver gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

8 April 2019

stated in

Crystal structure of human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

8 April 2019

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IBA

cell component

cytoplasm

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

cytosol

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

TAS

extracellular exosome

determination method

IDA

2 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

mitochondrion

determination method

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

mitochondrion

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IBA

extracellular exosome

determination method

HDA

1 reference

retrieved

8 April 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

HDA

biological process

carnitine biosynthetic process

determination method

IDA

IEA

TAS

5 references

retrieved

26 September 2017

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

TAS

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

26 September 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

26 September 2017

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

26 September 2017

stated in

Crystal structure of human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75936&geneProductId=UniProtKB:O75936

determination method

IDA

carnitine biosynthetic process

determination method

IBA

IDA

IEA

TAS

6 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IEA

retrieved

8 April 2019

stated in

Crystal structure of human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

8 April 2019

stated in

Carnitine biosynthesis: identification of the cDNA encoding human gamma-butyrobetaine hydroxylase

GOA

curator

UniProt

UniProt protein ID

O75936

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75936

determination method

IBA

Gene Atlas image

PBB GE BBOX1 205363 at fs.png
732 × 530; 10 KB

0 references

has part(s)

Gamma-butyrobetaine hydroxylase-like, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75936

TauD/TfdA-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75936

Identifiers

MeSH descriptor ID

D050563

subject named as

gamma-Butyrobetaine Dioxygenase

0 references

MeSH tree code

D08.811.682.690.708.401

0 references

RefSeq protein ID

NP_003977

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8424

XP_011518704

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8424

NP_001363187

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8424

NP_001363188

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8424

NP_001363189

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8424

NP_001363190

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8424

UniProt protein ID

O75936

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O75936

Ensembl protein ID

ENSP00000263182

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000263182

ENSP00000433772

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000433772

ENSP00000434918

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000434918

ENSP00000435781

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000435781

ENSP00000435369

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000435369

Freebase ID

/m/03crzqx

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

3MS5

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

3N6W

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

3O2G

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4BG1

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4BGK

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4BGM

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4BHF

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4BHG

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4BHI

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4C5W

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4C8R

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

4CWD

1 reference

stated in

UniProt

UniProt protein ID

O75936

retrieved

9 August 2016

language of work or name

English

UMLS CUI

C0061031

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q3266583&oldid=2022904303"