Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease (Q33112256)

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English	Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease	scientific article

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scholarly article

1 reference

Europe PubMed Central

19 July 2017

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease (English)

1 reference

Europe PubMed Central

19 July 2017

Parkinson's disease

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integrin subunit beta 2

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GOA release 2020-03-11

positive regulation of prostaglandin-E synthase activity

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GOA release 2020-03-11

Integrin alpha-M

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GOA release 2020-03-11

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based on heuristic

inferred from title

neurodegeneration

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based on heuristic

inferred from title

12

object named as

Jing Zhang

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Europe PubMed Central

19 July 2017

Michelle L. Block

13

object named as

Michelle L Block

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Europe PubMed Central

19 July 2017

author name string

Xiaoming Hu

1

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Europe PubMed Central

19 July 2017

Dan Zhang

2

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Europe PubMed Central

19 July 2017

Hao Pang

3

1 reference

Europe PubMed Central

19 July 2017

W Michael Caudle

4

1 reference

Europe PubMed Central

19 July 2017

Yachen Li

5

1 reference

Europe PubMed Central

19 July 2017

Huiming Gao

6

1 reference

Europe PubMed Central

19 July 2017

Yuxin Liu

7

1 reference

Europe PubMed Central

19 July 2017

Li Qian

8

1 reference

Europe PubMed Central

19 July 2017

Belinda Wilson

9

1 reference

Europe PubMed Central

19 July 2017

Donato A Di Monte

10

1 reference

Europe PubMed Central

19 July 2017

Syed F Ali

11

1 reference

Europe PubMed Central

19 July 2017

Jau-Shyong Hong

14

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Europe PubMed Central

19 July 2017

language of work or name

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publication date

1 November 2008

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Europe PubMed Central

19 July 2017

Journal of Immunology

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Europe PubMed Central

19 July 2017

181

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Europe PubMed Central

19 July 2017

10

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Europe PubMed Central

19 July 2017

7194-7204

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Europe PubMed Central

19 July 2017

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759089

14 July 2018

Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration

1 reference

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14 July 2018

Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein.

1 reference

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The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease

1 reference

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

1 reference

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14 July 2018

3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.

1 reference

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14 July 2018

Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.

1 reference

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The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides

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Microglial activation induced by neurodegeneration: a proteomic analysis

1 reference

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Neutrophil beta2 integrins: moderators of life or death decisions

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Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia.

1 reference

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Effects of blocking the dopamine biosynthesis and of neurotoxic dopamine depletion with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on voluntary wheel running in mice

1 reference

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Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase

1 reference

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14 July 2018

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

1 reference

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1 reference

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Regulating factors for microglial activation

1 reference

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Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat

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Parkinson's disease: clinical signs and symptoms, neural mechanisms, positron emission tomography, and therapeutic interventions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759089

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CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression

1 reference

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1 reference

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1 reference

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'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils

1 reference

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Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

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NADPH oxidase: an update

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Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor

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Integrin Mac-1 and beta-amyloid in microglial release of nitric oxide.

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Expression of a soluble and functional form of the human beta 2 integrin CD11b/CD18

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Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18981141

12 December 2020

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Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18981141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of class IA phosphoinositide 3-kinase in neutrophils prevents NADPH oxidase activation- and adhesion-dependent inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18981141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls

1 reference

https://pubmed.ncbi.nlm.nih.gov/18981141

12 December 2020

based on heuristic

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MPTP-induced oxidative stress and neurotoxicity are age-dependent: evidence from measures of reactive oxygen species and striatal dopamine levels

1 reference

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Interferon-gamma induces microglial-activation-induced cell death: a hypothetical mechanism of relapse and remission in multiple sclerosis

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Identifiers

10.4049/JIMMUNOL.181.10.7194

1 reference

Europe PubMed Central

19 July 2017

1 reference

Europe PubMed Central

19 July 2017

1 reference

Europe PubMed Central

19 July 2017

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