CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers (Q33112679)

19 July 2017

title

CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers (English)

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19 July 2017

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GOA release 2020-03-11

Adrian C Hayday

2

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author name string

Dick John Pang

series ordinal

1

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19 July 2017

Marie-José Bijlmakers

series ordinal

3

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19 July 2017

language of work or name

English

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publication date

6 March 2007

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Journal of Biological Chemistry

19 July 2017

published in

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19 July 2017

volume

282

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19 July 2017

issue

18

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19 July 2017

page(s)

13884-13894

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The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex

19 July 2017

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MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

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CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

21 January 2018

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Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling

21 January 2018

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HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains

21 January 2018

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CD4 receptor localized to non-raft membrane microdomains supports HIV-1 entry. Identification of a novel raft localization marker in CD4.

21 January 2018

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21 January 2018

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Insolubility of lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts).

21 January 2018

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

21 January 2018

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Lipid domain structure of the plasma membrane revealed by patching of membrane components

21 January 2018

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GPI-anchored proteins are organized in submicron domains at the cell surface.

21 January 2018

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Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

21 January 2018

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Phospholipids undergo hop diffusion in compartmentalized cell membrane

21 January 2018

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Lipid raft domains and protein networks in T-cell receptor signal transduction

21 January 2018

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Location is everything: lipid rafts and immune cell signaling.

21 January 2018

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21 January 2018

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Membrane compartmentation is required for efficient T cell activation.

21 January 2018

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S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

21 January 2018

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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

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Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

21 January 2018

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Condensation of the plasma membrane at the site of T lymphocyte activation

21 January 2018

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21 January 2018

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CD4 raft association and signaling regulate molecular clustering at the immunological synapse site

21 January 2018

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The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR co-receptor CD8alphabeta

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Requirement for CD8 beta chain in positive selection of CD8-lineage T cells

21 January 2018

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T cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL.

21 January 2018

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The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory

21 January 2018

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Generation of anti-human CD8β-specific antibodies using transfectants expressing mixed-species CD8 heterodimers

21 January 2018

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Human CD8 beta, but not mouse CD8 beta, can be expressed in the absence of CD8 alpha as a beta beta homodimer

21 January 2018

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Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

21 January 2018

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The on-off story of protein palmitoylation

21 January 2018

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21 January 2018

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Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

21 January 2018

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Primary sequence requirements for S-acylation of beta(2)-adrenergic receptor peptides

21 January 2018

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N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae

21 January 2018

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Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain

21 January 2018

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Palmitoylation and intracellular domain interactions both contribute to raft targeting of linker for activation of T cells

21 January 2018

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Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins

21 January 2018

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Association of GAP-43 with detergent-resistant membranes requires two palmitoylated cysteine residues

21 January 2018

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Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M701027200

1 reference

19 July 2017

1 reference