Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1. (Q33183063)

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English	Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1.	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1 (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

author name string

H Kawagoe

1

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2 December 2019

R Kawagoe

2

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2 December 2019

K Sano

3

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2 December 2019

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1 November 2001

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2 December 2019

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2 December 2019

15

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2 December 2019

11

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2 December 2019

1743-1749

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2 December 2019

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

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The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

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7 January 2021

based on heuristic

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Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

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Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

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11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

1 reference

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7 January 2021

based on heuristic

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Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene

1 reference

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7 January 2021

based on heuristic

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The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

1 reference

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7 January 2021

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The FEL (AF-4) protein donates transcriptional activation sequences to Hrx-Fel fusion proteins in leukemias containing T(4;11)(Q21;Q23) chromosomal translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

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Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia

1 reference

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7 January 2021

based on heuristic

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An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

1 reference

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7 January 2021

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Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

1 reference

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7 January 2021

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Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia

1 reference

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7 January 2021

based on heuristic

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Altered Hox expression and segmental identity in Mll-mutant mice

1 reference

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7 January 2021

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Homeo boxes in the study of development

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Murine developmental control genes

1 reference

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The murine and Drosophila homeobox gene complexes have common features of organization and expression.

1 reference

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7 January 2021

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Vertebrate homeobox gene nomenclature

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7 January 2021

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The role of HOX homeobox genes in normal and leukemic hematopoiesis

1 reference

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Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

1 reference

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Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia

1 reference

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7 January 2021

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

1 reference

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7 January 2021

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Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)

1 reference

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7 January 2021

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Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

1 reference

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7 January 2021

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Lineage and stage specific expression of HOX 1 genes in the human hematopoietic system

1 reference

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

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The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator

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Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods

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Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

1 reference

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The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

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