Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells (Q33183622)

23 July 2017

Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells (English)

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23 July 2017

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Thilo Hagen

1

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23 July 2017

Elena Di Daniel

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2

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23 July 2017

Ainsley A Culbert

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3

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23 July 2017

Alastair D Reith

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4

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23 July 2017

language of work or name

English

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publication date

19 April 2002

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Journal of Biological Chemistry

23 July 2017

6

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based on heuristic

inferred from page(s)

published in

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23 July 2017

277

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23 July 2017

26

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23 July 2017

23330-23335

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Signal transduction by the Wnt family of ligands

23 July 2017

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

Wnt signalling: pathway or network?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

GSK3, a master switch regulating cell-fate specification and tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

GSK3 takes centre stage more than 20 years after its discovery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Regulation of GSK-3: a cellular multiprocessor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

beta-catenin is a target for the ubiquitin-proteasome pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201364200

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Predominant mutation of codon 41 of the beta-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Structure of GSK3beta reveals a primed phosphorylation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

Differential molecular assemblies underlie the dual function of Axin in modulating the WNT and JNK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201364200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201364200

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23 July 2017

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