Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine (Q33186856)

23 July 2017

Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine (English)

1 reference

23 July 2017

4

Władysława A Daniel

1 reference

23 July 2017

1

Jacek Wójcikowski

1 reference

23 July 2017

Lydiane Pichard-Garcia

series ordinal

2

1 reference

PubMed ID

12721102

23 July 2017

Patrick Maurel

series ordinal

3

1 reference

PubMed ID

12721102

23 July 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

British Journal of Pharmacology

23 July 2017

1 reference

23 July 2017

138

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23 July 2017

8

1 reference

23 July 2017

1465-1474

1 reference

The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics

23 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Effects of selective cytochrome P-450 inhibitors on the metabolism of thioridazine. In vitro studies.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

The influence of selective serotonin reuptake inhibitors on the plasma and brain pharmacokinetics of the simplest phenothiazine neuroleptic promazine in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Promazine pharmacokinetics during concurrent treatment with tricyclic antidepressants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Effect of carbamazepine on the pharmacokinetics of promazine.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

The effects of selective serotonin reuptake inhibitors and their metabolites on S-mephenytoin 4'-hydroxylase activity in human liver microsomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

The pharmacokinetics of promazine and its metabolites after acute and chronic administration to rats--a comparison with the pharmacokinetics of imipramine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Metabolism of thioridazine by microsomal monooxygenases: relative roles of P450 and flavin-containing monooxygenase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Antagonism by neuroleptics of neurotransmitter receptors of normal human brain in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Relationship of neuroleptic drug effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Quantitative assay for albumin-producing liver cells after simian virus 40 transformation of rat hepatocytes maintained in chemically defined medium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

HPLC with electrochemical detection to measure chlorpromazine, thioridazine and metabolites in human brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Species variation in the response of the cytochrome P-450-dependent monooxygenase system to inducers and inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Brain receptors for antipsychotic drugs and dopamine: direct binding assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Metabolism and excretion of promazine by the horse.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705195

Stereo- and regioselective N- and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573803

Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine

31 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705195

Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in human beings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705195

The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705195

Inhibition of desipramine 2-hydroxylation by quinidine and quinine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705195

N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705195

Fluvoxamine is a potent inhibitor of cytochrome P4501A2

21 January 2018

1 reference

12 December 2020

Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver

1 reference

12 December 2020

Changes in amounts of cytochrome P450 isozymes and levels of catalytic activities in hepatic and renal microsomes of rats with streptozocin-induced diabetes

1 reference

12 December 2020

Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine

1 reference

12 December 2020

Effect of antipsychotic drugs on human liver cytochrome P-450 (CYP) isoforms in vitro: preferential inhibition of CYP2D6

1 reference

12 December 2020

Identification of human cytochrome P450 isoforms involved in the 7-hydroxylation of chlorpromazine by human liver microsomes

1 reference

12 December 2020

Side-chain degradation and ring hydroxylation of pehnothiazine tranquilizers

1 reference

12 December 2020

The metabolism of promazine and acetylpromazine in the horse

1 reference

12 December 2020

Convenient oxidation of phenothiazine salts to their sulfoxides with aqueous nitrous acid

1 reference

12 December 2020

Pharmacokinetics of promazine: I. Disposition in patients with acute viral hepatitis B

1 reference

12 December 2020

Clinical implications of slow sulphoxidation of thioridazine in a poor metabolizer of the debrisoquine type

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0705195

1 reference

23 July 2017

1 reference

23 July 2017

1 reference

PubMed ID

12721102