High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate (Q33187699)

23 July 2017

High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate (English)

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high-throughput screening

23 July 2017

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Michela Zolli-Juran

1

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23 July 2017

Jonathan D Cechetto

2

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23 July 2017

Rebecca Hartlen

3

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23 July 2017

Denis M Daigle

4

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23 July 2017

Eric D Brown

5

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23 July 2017

language of work or name

English

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publication date

1 August 2003

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Bioorganic & Medicinal Chemistry Letters

23 July 2017

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23 July 2017

13

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23 July 2017

15

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23 July 2017

2493-2496

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The methotrexate story: a paradigm for development of cancer chemotherapeutic agents.

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Identification of critical amino acid residues on human dihydrofolate reductase protein that mediate RNA recognition

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Effect of substrate decomposition on the spectrophotometric assay of dihydrofolate reductase

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues

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Inhibition of dihydrofolate reductase: effect of reduced nicotinamide adenine dinucleotide phosphate on the selectivity and affinity of diaminobenzylpyrimidines

1 reference

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Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines

1 reference

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X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor

1 reference

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Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

1 reference

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7 January 2021

10.1016/S0960-894X(03)00480-3

Identifiers

DOI

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23 July 2017

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