NHE-1 inhibition: from protection during acute ischaemia/reperfusion to prevention/reversal of myocardial remodelling (Q33193200)

23 July 2017

1 reference

title

NHE-1 inhibition: from protection during acute ischaemia/reperfusion to prevention/reversal of myocardial remodelling (English)

1 reference

23 July 2017

1 reference

https://api.crossref.org/works/10.1007/S00210-003-0808-2

13 March 2024

author name string

Wolfgang J. Linz

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504689

13 March 2024

Andreas E. Busch

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504689

13 March 2024

language of work or name

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19 September 2003

1 reference

full work available at URL

23 July 2017

https://link.springer.com/content/pdf/10.1007%2Fs00210-003-0808-2.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504689

http://link.springer.com/content/pdf/10.1007/s00210-003-0808-2.pdf

13 March 2024

file format

Portable Document Format

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1007/S00210-003-0808-2

http://link.springer.com/article/10.1007/s00210-003-0808-2/fulltext.html

13 March 2024

1 reference

https://api.crossref.org/works/10.1007/S00210-003-0808-2

http://link.springer.com/content/pdf/10.1007/s00210-003-0808-2

13 March 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1007/S00210-003-0808-2

Naunyn-Schmiedeberg's Archives of Pharmacology

13 March 2024

published in

1 reference

23 July 2017

volume

368

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23 July 2017

issue

4

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23 July 2017

page(s)

239-246

1 reference

Tissue distribution of Na+/H+ exchanger isoforms NHE2 and NHE4 in rat intestine and kidney.

23 July 2017

cites work

1 reference

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A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections

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Diabetes-induced vascular hypertrophy is accompanied by activation of Na(+)-H(+) exchange and prevented by Na(+)-H(+) exchange inhibition

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Pharmacological interference with the cardiac renin-angiotensin system

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Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium

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Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate.

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Na(+)/H(+) exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium

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Inhibition of the Na(+)/H(+) exchanger delays the development of rapid pacing-induced atrial contractile dysfunction

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Protection of the ischaemic myocardium by Na+/H+ exchange inhibitors: potential mechanisms of action

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The expanding family of eucaryotic Na(+)/H(+) exchangers

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Differential effects of angiotensin AT1 and AT2 receptors on the expression, translation and function of the Na+-H+ exchanger and Na+-HCO3- symporter in the rat heart after myocardial infarction

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Regression of hypertensive myocardial fibrosis by Na(+)/H(+) exchange inhibition

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12 December 2020

NHE1-inhibitor cariporide prevents the transient reperfusion-induced shortening of the monophasic action potential after coronary ischemia in pigs

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12 December 2020

Do NHE inhibition and ischemic preconditioning convey cardioprotection through a common mechanism?

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12 December 2020

GUARD During Ischemia Against Necrosis (GUARDIAN) trial in acute coronary syndromes

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12 December 2020

Identification of a mitochondrial Na+/H+ exchanger

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12 December 2020

Effective protection by NHE-1 inhibition in ischemic and reperfused heart under preconditioning blockade

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12 December 2020

Activation of Na(+)-H+ antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system

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12 December 2020

Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects

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12 December 2020

Pharmacological profile of SL 59.1227, a novel inhibitor of the sodium/hydrogen exchanger

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12 December 2020

Na/H exchange isoform 1 is involved in mineralocorticoid/salt-induced cardiac injury

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12 December 2020

Modulation of Na+/H+ exchange isoform 1 mRNA expression in isolated rat hearts

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12 December 2020

Heterotrimeric G proteins in heart disease

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12 December 2020

Thrombin activates the sarcolemmal Na(+)-H+ exchanger. Evidence for a receptor-mediated mechanism involving protein kinase C

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12 December 2020

Effects of cariporide and losartan on hypertrophy, calcium transients, contractility, and gene expression in congestive heart failure

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12 December 2020

Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria

1 reference

12 December 2020

Calmodulin-binding autoinhibitory domain controls "pH-sensing" in the Na+/H+ exchanger NHE1 through sequence-specific interaction

1 reference

12 December 2020

Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs

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12 December 2020

Influence of endothelin 1 on human atrial myocardium--myocardial function and subcellular pathways

1 reference

12 December 2020

Hypertrophic responsiveness of cardiomyocytes to alpha- or beta-adrenoceptor stimulation requires sodium-proton-exchanger-1 (NHE-1) activation but not cellular alkalization

1 reference

12 December 2020

Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2).

1 reference

12 December 2020

Regulation of intracellular pH in cultured hippocampal neurons by an amiloride-insensitive Na+/H+ exchanger

1 reference

12 December 2020

Na+/H+ exchangers of mammalian cells.

1 reference

12 December 2020

Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide

1 reference

12 December 2020

Bradykinin B1 and B2 receptors differentially regulate cardiac Na+-H+ exchanger, Na+-Ca2+ exchanger and Na+-HCO3- symporter

1 reference

12 December 2020

Myocardial protection during ventricular fibrillation by inhibition of the sodium-hydrogen exchanger isoform-1.

1 reference

12 December 2020

Aldosterone modulates both the Na/H antiport and Cl/HCO3 exchanger in cultured neonatal rat cardiac cells

1 reference

12 December 2020

NHE2 and NHE3 are human and rabbit intestinal brush-border proteins

1 reference

12 December 2020

Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy

1 reference

12 December 2020

Renal expression of novel Na+/H+ exchanger isoform NHE8

1 reference

12 December 2020

Development of the Na+/H+ exchange inhibitor cariporide as a cardioprotective drug: from the laboratory to the GUARDIAN trial

1 reference

12 December 2020

Contributions of endothelin-1 and sodium hydrogen exchanger-1 in the diabetic myocardium.

1 reference

12 December 2020

NHE3: a Na+/H+ exchanger isoform of renal brush border

1 reference

12 December 2020

Role of sodium-hydrogen exchange in cardiac hypertrophy and heart failure: a novel and promising therapeutic target

1 reference

12 December 2020

Na(+)/H(+) exchange inhibitors for cardioprotective therapy: progress, problems and prospects

1 reference

12 December 2020

Induction of expression of the sodium-hydrogen exchanger in rat myocardium

1 reference

12 December 2020

Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model

1 reference

12 December 2020

Pharmacological analysis by HOE642 and KB-R9032 of the role of Na(+)/H(+) exchange in the endothelin-1-induced Ca(2+) signalling in rabbit ventricular myocytes

1 reference

12 December 2020

Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network

1 reference

12 December 2020

Sodium-hydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability

1 reference

12 December 2020

Regression of cardiomyocyte hypertrophy in SHR following chronic inhibition of the Na(+)/H(+) exchanger

1 reference

12 December 2020

Na(+)/H(+)exchangers: linking osmotic dysequilibrium to modified cell function

1 reference

12 December 2020

Glucose metabolism, H+ production and Na+/H+-exchanger mRNA levels in ischemic hearts from diabetic rats

1 reference

12 December 2020

The Na-H exchanger revisited: an update on Na-H exchange regulation and the role of the exchanger in hypertension and cardiac function in health and disease

1 reference

12 December 2020

A novel topology model of the human Na(+)/H(+) exchanger isoform 1

1 reference

12 December 2020

Protein kinase-mediated regulation of the Na(+)/H(+) exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways

1 reference

12 December 2020

Regulation of cardiac sarcolemmal Na+/H+ exchanger activity: potential pathophysiological significance of endogenous mediators and oxidant stress

1 reference

12 December 2020

Na+/H+ exchange hyperactivity and myocardial hypertrophy: are they linked phenomena?

1 reference

12 December 2020

The effect of an Na+/H+ exchange inhibitor, SM-20550, on ischemia/reperfusion-induced endothelial dysfunction in isolated perfused rat hearts.

1 reference

12 December 2020

Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice

1 reference

12 December 2020

Adenosine A(1) receptor stimulation inhibits alpha(1)-adrenergic activation of the cardiac sarcolemmal Na(+)/H(+) exchanger

1 reference

12 December 2020

The Na+/H+ exchanger gene family

1 reference

12 December 2020

Long-term ACE inhibition doubles lifespan of hypertensive rats

1 reference

12 December 2020

MRI/MRS evaluation of cariporide in a canine long-term model of reperfused ischemic insults. Magnetic resonance imaging/magnetic resonance spectroscopy

1 reference

12 December 2020

Na(+)/H(+) exchange inhibitor cariporide attenuates cell injury predominantly during ischemia and not at onset of reperfusion in porcine hearts with low residual blood flow

1 reference

12 December 2020

The p42/p44 mitogen-activated protein kinase cascade is determinant in mediating activation of the Na+/H+ exchanger (NHE1 isoform) in response to growth factors

1 reference

12 December 2020

Cardioprotective effects of the Na(+)/H(+)-exchange inhibitor cariporide in infarct-induced heart failure

1 reference

12 December 2020

High-performance liquid chromatographic analysis of free hydroxyproline and proline in blood plasma and of free and peptide-bound hydroxyproline in urine

1 reference

12 December 2020

The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial

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12 December 2020

Functional and cellular regulation of the myocardial Na+/H+ exchanger

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12 December 2020

Myocardial protection during ventricular fibrillation by reduction of proton-driven sarcolemmal sodium influx

1 reference

12 December 2020

Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.

1 reference

12 December 2020

Effects of the Na+/H+ exchange inhibitor cariporide (HOE 642) on cardiac function and cardiomyocyte cell death in rat ischaemic-reperfused heart

1 reference

12 December 2020

Dose-dependent reduction of myocardial infarct mass in rabbits by the NHE-1 inhibitor cariporide (HOE 642).

1 reference

12 December 2020

Pharmacokinetic/pharmacodynamic evaluation of the NHE inhibitor eniporide

1 reference

12 December 2020

Inhibition of the Na(+)/H(+) exchanger attenuates phase 1b ischemic arrhythmias and reperfusion-induced ventricular fibrillation

1 reference

12 December 2020

Activation of protein kinase cascades in the heart by hypertrophic G protein-coupled receptor agonists

1 reference

12 December 2020

Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

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12 December 2020

The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease

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12 December 2020

Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators

1 reference

12 December 2020

A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo.

1 reference

12 December 2020

Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1).

1 reference

12 December 2020

p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2

1 reference

12 December 2020

Phosphorylation and regulation of the Na+/H+ exchanger through mitogen-activated protein kinase

1 reference

12 December 2020

Potent and selective inhibition of the human Na+/H+ exchanger isoform NHE1 by a novel aminoguanidine derivative T-162559.

1 reference

12 December 2020

Na(+)/H(+) exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats

1 reference

12 December 2020

A 90-kD Na(+)-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells

1 reference

12 December 2020

Calcium and osmotic regulation of the Na+/H+ exchanger in neonatal ventricular myocytes

1 reference

12 December 2020

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

1 reference

12 December 2020

Influence of pHi and creatine phosphate on alpha-adrenoceptor-mediated cardiac hypertrophy

1 reference

12 December 2020

Identifiers

DOI

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Dimensions Publication ID

23 July 2017

1019818724

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