Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton (Q33213467)

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English	Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 July 2017

Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton (English)

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Europe PubMed Central

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24 July 2017

apoptotic process

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author name string

Chamaon K

1

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Europe PubMed Central

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24 July 2017

Stojek J

2

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24 July 2017

Kanakis D

3

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Europe PubMed Central

PubMed publication ID

24 July 2017

Braeuninger S

4

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Europe PubMed Central

PubMed publication ID

24 July 2017

Kirches E

5

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Europe PubMed Central

PubMed publication ID

24 July 2017

Krause G

6

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24 July 2017

Mawrin C

7

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Europe PubMed Central

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24 July 2017

Dietzmann K

8

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24 July 2017

publication date

1 March 2005

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24 July 2017

Journal of Neuro-Oncology

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24 July 2017

72

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24 July 2017

1

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24 July 2017

11-16

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24 July 2017

The effect of endogenous estradiol metabolites on the proliferation of human breast cancer cells

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel 2-methoxyestradiol analogues with antitumor activity

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors alpha and beta

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-methoxyestradiol-induced growth suppression and lethality in estrogen-responsive MCF-7 cells may be mediated by down regulation of p34cdc2 and cyclin B1 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines.

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site

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https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl2 is the guardian of microtubule integrity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol

1 reference

https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15803369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11060-004-2158-4

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Europe PubMed Central

PubMed publication ID

24 July 2017

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

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