Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition (Q33218209)

24 July 2017

title

Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition (English)

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5

Andrea M Hujer

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12

Robert A Bonomo

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Deley Sulton

1

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Doritza Pagan-Rodriguez

2

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Xiang Zhou

3

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Yiding Liu

4

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Christopher R Bethel

6

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Marion S Helfand

7

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Jodi M Thomson

8

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Vernon E Anderson

9

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John D Buynak

10

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Lily M Ng

11

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language of work or name

English

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publication date

29 June 2005

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Journal of Biological Chemistry

24 July 2017

published in

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volume

280

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issue

42

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page(s)

35528-35536

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Beta-lactamases: a survey of protein diversity

24 July 2017

cites work

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Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

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21 January 2018

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X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid

21 January 2018

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The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34

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Molecular dynamics at the root of expansion of function in the M69L inhibitor-resistant TEM beta-lactamase from Escherichia coli

21 January 2018

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Following the Reactions of Mechanism-Based Inhibitors with β-Lactamase by Raman Crystallography

21 January 2018

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Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.

21 January 2018

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Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam

21 January 2018

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Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure

21 January 2018

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Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition

21 January 2018

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Kinetic interactions of tazobactam with beta-lactamases from all major structural classes

21 January 2018

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Inhibition of TEM-2 beta-lactamase from Escherichia coli by clavulanic acid: observation of intermediates by electrospray ionization mass spectrometry.

21 January 2018

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A semi-synthetic penicillinase inactivator

21 January 2018

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Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant

21 January 2018

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Inhibition of Class A and Class C β-Lactamases by Penems: Crystallographic Structures of a Novel 1,4-Thiazepine Intermediate,

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M501251200

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24 July 2017

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