Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma (Q33224524)

24 July 2017

Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma (English)

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24 July 2017

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Laurent Brard

1

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author name string

Cornelius O Granai

series ordinal

2

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PubMed ID

16203029

24 July 2017

Narasimha Swamy

series ordinal

3

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PubMed ID

16203029

24 July 2017

language of work or name

English

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publication date

3 October 2005

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24 July 2017

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24 July 2017

100

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24 July 2017

1

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24 July 2017

116-127

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24 July 2017

Cancer statistics, 2004

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Moderate progress for ovarian cancer in the last 20 years: prolongation of survival, but no improvement in the cure rate.

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Iron metabolism--new perspectives in view

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Iron-induced carcinogenesis: the role of redox regulation

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Iron, asbestos, and carcinogenicity

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Iron chelators as therapeutic agents for the treatment of cancer.

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Iron deprivation-induced apoptosis in HL-60 cells

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Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells

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Iron reverses impermeable chelator inhibition of DNA synthesis in CCl 39 cells

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Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions.

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Involvement of intracellular glutathione in zinc deficiency-induced activation of hepatic stellate cells

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Radiolabeled peptides in the diagnosis and therapy of oncological diseases

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Pharmacotherapy of iron overload in thalassaemic patients

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Effect of iron and desferoxamine on cell growth and in vitro ferritin synthesis in human hepatoma cell lines

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1 reference

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Direct evidence that iron deprivation induces apoptosis in murine lymphoma 38C13

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Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

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Development and characterization of a clinically useful animal model of epithelial ovarian cancer in the Fischer 344 rat.

7 January 2021

1 reference

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Use of MTT colorimetric assay to measure cell activation.

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Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication

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The ribonucleotide reductase inhibitor trimidox induces c-myc and apoptosis of human ovarian carcinoma cells

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Assays of cell viability: discrimination of cells dying by apoptosis.

7 January 2021

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Mitogen-activated protein kinase pathway mediates DBP-maf-induced apoptosis in RAW 264.7 macrophages.

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

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The role of iron chelation in cancer therapy

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Cancer statistics, 2002

1 reference

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Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer

7 January 2021

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Iron chelators in cancer chemotherapy

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Iron chelator research: past, present, and future

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Desferrithiocin is a more potent antineoplastic agent than desferrioxamine.

7 January 2021

1 reference

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Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes

7 January 2021

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Chemoresistance in human ovarian cancer: the role of apoptotic regulators

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Iron chelators induce apoptosis in proliferating cells

7 January 2021

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Iron-chelating agents in non-iron overload conditions

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Deferoxamine, cyclophosphamide, etoposide, carboplatin, and thiotepa (D-CECaT): a new cytoreductive chelation-chemotherapy regimen in patients with advanced neuroblastoma

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Deferoxamine followed by cyclophosphamide, etoposide, carboplatin, thiotepa, induction regimen in advanced neuroblastoma: preliminary results. Italian Neuroblastoma Cooperative Group

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1 reference

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Effect of iron chelators on proliferation and iron uptake in hepatoma cells

7 January 2021

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The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression

7 January 2021

1 reference

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Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.

7 January 2021

1 reference

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Activation of caspase pathways during iron chelator-mediated apoptosis

7 January 2021

1 reference

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Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine

7 January 2021

1 reference

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Therapeutic potential of iron chelators in cancer therapy

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https://api.crossref.org/works/10.1016%2FJ.YGYNO.2005.07.129

inferred from DOI database lookup

7 January 2021

based on heuristic

Secondary iron overload

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2005.07.129

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YGYNO.2005.07.129

1 reference

24 July 2017

1 reference

PubMed ID

16203029