Beyond monoamines: glutamatergic function in mood disorders (Q33231128)

24 July 2017

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title

Beyond monoamines: glutamatergic function in mood disorders (English)

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24 July 2017

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2

Gerard Sanacora

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24 July 2017

Akira Kugaya

1

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24 July 2017

1 October 2005

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24 July 2017

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24 July 2017

10

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24 July 2017

808-819

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24 July 2017

10

1 reference

Controlled trial of amantadine hydrochloride in Parkinson's disease.

24 July 2017

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

The NR1 subunit of the glutamate/NMDA receptor in the superior temporal cortex in schizophrenia and affective disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Neuronal glutamate uptake Contributes to GABA synthesis and inhibitory synaptic strength.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Low glial numbers in the amygdala in major depressive disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

The Yin and Yang of NMDA receptor signalling

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Lamotrigine as adjunct to paroxetine in acute depression: a placebo-controlled, double-blind study

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Neurochemistry of late-life major depression: a pilot two-dimensional MR spectroscopic study

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant effects of ketamine in depressed patients

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Amantadine as augmentation therapy in the management of treatment-resistant depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

LY404187: A Novel Positive Allosteric Modulator of AMPA Receptors

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7 January 2021

Involvement of the sigma 1 receptor in the modulation of dopaminergic transmission by amantadine

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https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Review of the use of topiramate for treatment of bipolar disorders

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https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Brain metabolic alterations in medication-free patients with bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A molecular and cellular theory of depression

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https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Treatment-refractory depression: Definitions and characteristics

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

GABA and glutamate systems as therapeutic targets in depression and mood disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Increased cortical GABA concentrations in depressed patients receiving ECT.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Lamotrigine as an augmentation agent in treatment-resistant depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Impairment of GABAergic transmission in depression: new insights from neuroimaging studies

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Amantadine in depression.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Benzodiazepines as antidepressants: does GABA play a role in depression?

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant-like effects of a partial agonist at strychnine-insensitive glycine receptors and a competitive NMDA receptor antagonist.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Cyloserine as an antidepressant agent

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Lamotrigine update and its use in mood disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Prolonged effect of an anesthetic dose of ketamine on behavioral despair

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A Double-Blind, Randomized, Placebo-Controlled Trial of Augmentation With Lamotrigine or Placebo in Patients Concomitantly Treated With Fluoxetine for Resistant Major Depressive Episodes

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

1-aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Recent developments in the psychobiology and pharmacotherapy of depression: optimising existing treatments and novel approaches for the future

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Glial fibrillary acidic protein immunoreactivity in the prefrontal cortex distinguishes younger from older adults in major depressive disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Neurotrophic effects of electroconvulsive therapy: a proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Pathways to neuronal injury and apoptosis in HIV-associated dementia.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

NMDA receptor antagonist treatment induces a long-lasting increase in the number of proliferating cells, PSA-NCAM-immunoreactive granule neurons and radial glia in the adult rat dentate gyrus

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Riluzole enhances glutamate uptake in rat astrocyte cultures

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Effects of MK-801 and antidepressant drugs in the forced swimming test in rats

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Novel neurotransmitters and their neuropsychiatric relevance

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Treatment of Impaired Cerebral Function in Psychogeriatric Patients with Memantine - Results of a Phase II Double-Blind Study

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Molecular pharmacology of glutamate transporters, EAATs and VGLUTs

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Inhibition of non‐vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Mind glue: implications of glial cell biology for psychiatry

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant-like actions of an AMPA receptor potentiator (LY392098).

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

GLIA: listening and talking to the synapse

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressants for the new millennium

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Glutamate toxicity in chronic neurodegenerative disease.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Increased serum glutamate in depressed patients

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Plasma and platelet excitatory amino acids in psychiatric disorders.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Dizocilpine antagonizes the effect of chronic imipramine on learned helplessness in rats.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Plasma and platelet amino acid concentrations in patients affected by major depression and under fluvoxamine treatment

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Brain amino acid concentrations and Ca2+-dependent release in intractable depression assessed antemortem

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A Double-Blind, Placebo-Controlled, Prophylaxis Study of Lamotrigine in Rapid-Cycling Bipolar Disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Alterations in the N-methyl-d-asparatate (NMDA) receptor complex in the frontal cortex of suicide victims

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Low nNOS protein in the locus coeruleus in major depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reduced anterior cingulate cortex glutamatergic concentrations in childhood major depression.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Decreased hippocampal NMDA, but not kainate or AMPA receptors in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Evidence that the N-methyl-D-aspartate subunit 1 receptor gene (GRIN1) confers susceptibility to bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A rating scale for depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Glial reduction in the subgenual prefrontal cortex in mood disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Possible use of amantadine in depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Current perspectives on the development of non-biogenic amine-based antidepressants

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

D-cycloserine: a ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Control of synapse number by glia

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Novel treatments for bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Word recognition memory before and after successful treatment of depression.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

An open-label trial of riluzole in patients with treatment-resistant major depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Affinity of 1-aminoadamantanes for the σ binding site in post-mortem human frontal cortex

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Small-dose ketamine improves the postoperative state of depressed patients

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant effect of ketamine during ECT.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Lamotrigine in the treatment of bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Lamotrigine augmentation in unipolar depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

MK-801 and enantiomers: potential antidepressants or false positives in classical screening models?

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant-like properties of zinc in rodent forced swim test

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

A high prevalence of organ-specific autoimmunity in patients with bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Tiagabine for the treatment of generalized anxiety disorder: a randomized, open-label, clinical trial with paroxetine as a positive control.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Benzodiazepines in Depressive Disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Tiagabine in treatment refractory bipolar disorder: a clinical case series.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Diffusional extrasynaptic neurotransmission via glutamate and GABA.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Alterations of neuroplasticity in depression: the hippocampus and beyond.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Age-dependent reductions in the level of glial fibrillary acidic protein in the prefrontal cortex in major depression

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

Is diazepam an antidepressant?

1 reference

https://api.crossref.org/works/10.1017%2FS1092852900010403

7 January 2021

10.1017/S1092852900010403

Identifiers

DOI

1 reference

24 July 2017

1 reference

PubMed ID

16400244