Directed evolution of adeno-associated virus yields enhanced gene delivery vectors (Q33232270)

24 July 2017

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors (English)

1 reference

24 July 2017

0 references

0 references

0 references

Narendra Maheshri

1

1 reference

24 July 2017

James T Koerber

series ordinal

2

1 reference

24 July 2017

Brian K Kaspar

series ordinal

3

1 reference

24 July 2017

David V Schaffer

series ordinal

4

1 reference

24 July 2017

22 January 2006

1 reference

24 July 2017

1 reference

24 July 2017

24

1 reference

24 July 2017

198-204

1 reference

24 July 2017

2

1 reference

https://scigraph.springernature.com/pub.10.1038/nbt1182

24 July 2017

0 references

cites work

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

1 reference

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

21 January 2018

1 reference

Adeno-associated viruses undergo substantial evolution in primates during natural infections

21 January 2018

1 reference

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

21 January 2018

1 reference

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

21 January 2018

1 reference

Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial

21 January 2018

1 reference

The cryptic life style of adeno-associated virus

21 January 2018

1 reference

Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes

21 January 2018

1 reference

Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors

21 January 2018

1 reference

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

21 January 2018

1 reference

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

21 January 2018

1 reference

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

21 January 2018

1 reference

Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV).

21 January 2018

1 reference

Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure

21 January 2018

1 reference

Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection

21 January 2018

1 reference

Immune responses to adeno-associated virus and its recombinant vectors

21 January 2018

1 reference

Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain

21 January 2018

1 reference

Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain.

21 January 2018

1 reference

Infection Efficiency of Human and Mouse Embryonic Stem Cells Using Adenoviral and Adeno-Associated Viral Vectors

21 January 2018

1 reference

Viral-mediated gene transfer to mouse primary neural progenitor cells.

21 January 2018

1 reference

Quantitative analysis of the packaging capacity of recombinant adeno-associated virus

21 January 2018

1 reference

Insertional mutagenesis of AAV2 capsid and the production of recombinant virus

21 January 2018

1 reference

Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2.

21 January 2018

1 reference

Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell-surface receptors

21 January 2018

1 reference

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors

21 January 2018

1 reference

In vitro selection of viral vectors with modified tropism: the adeno-associated virus display

21 January 2018

1 reference

Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding

21 January 2018

1 reference

Structure of adeno-associated virus serotype 5.

21 January 2018

1 reference

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

21 January 2018

1 reference

Rapid evolution of a protein in vitro by DNA shuffling

21 January 2018

1 reference

Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine

21 January 2018

1 reference

Yeast surface display for screening combinatorial polypeptide libraries

21 January 2018

1 reference

Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies

21 January 2018

1 reference

Molecular breeding of viruses

21 January 2018

1 reference

Molecular evolution by staggered extension process (StEP) in vitro recombination

21 January 2018

1 reference

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

21 January 2018

1 reference

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

21 January 2018

1 reference

Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies

21 January 2018

1 reference

Clades of Adeno-associated viruses are widely disseminated in human tissues.

21 January 2018

1 reference

Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts

21 January 2018

1 reference

Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer

21 January 2018

1 reference

Transfer of high copy number plasmid into mammalian cells by calcium phosphate transfection

21 January 2018

1 reference

Identification of a heparin-binding motif on adeno-associated virus type 2 capsids

21 January 2018

1 reference

Nucleotide sequence and organization of the adeno-associated virus 2 genome

21 January 2018

1 reference

7 January 2021

Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector

1 reference

7 January 2021

Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants

1 reference

7 January 2021

Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2.

1 reference

7 January 2021

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

1 reference

7 January 2021

Structural studies on antibody interacting with viruses

1 reference

7 January 2021

Identifiers

DOI

10.1038/NBT1182

1 reference

24 July 2017

1 reference