Allosteric activation of the follicle-stimulating hormone (FSH) receptor by selective, nonpeptide agonists. (Q33236674)

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18 January 2020

title

Allosteric activation of the follicle-stimulating hormone (FSH) receptor by selective, nonpeptide agonists (English)

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2

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author name string

Stephen D Yanofsky

1

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18 January 2020

Frank Holden

3

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Erik Whitehorn

4

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Barbara Aguilar

5

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18 January 2020

Emily Tate

6

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Christopher P Holmes

7

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Randall Scheuerman

8

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Derek MacLean

9

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May M Wu

10

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18 January 2020

Donald E Frail

11

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Francisco J López

12

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Richard Winneker

13

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Brian J Arey

14

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Ronald W Barrett

15

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language of work or name

English

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publication date

15 March 2006

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Journal of Biological Chemistry

18 January 2020

published in

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volume

281

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issue

19

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page(s)

13226-13233

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Expression of the human follicle-stimulating hormone receptor in the baculovirus system

18 January 2020

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Development of a bioassay for FSH using a recombinant human FSH receptor and a cAMP responsive luciferase reporter gene.

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Functional analysis of the D2L dopamine receptor expressed in a cAMP-responsive luciferase reporter cell line

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Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure

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Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility

21 January 2018

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Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

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A generic method for the production of cell lines expressing high levels of 7-transmembrane receptors

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Influence of receptor number on the stimulation by salmeterol of gene transcription in CHO-K1 cells transfected with the human beta2-adrenoceptor

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Libraries of non-polymeric organic molecules

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Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions

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Agonists of the follicle stimulating hormone receptor from an encoded thiazolidinone library

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Versatile approach to encoding combinatorial organic syntheses using chemically robust secondary amine tags

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Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function

21 January 2018

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Extracellular domain chimeras of the TSH and LH/CG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding

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A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor [see commetns].

21 January 2018

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Small molecule biaryl FSH receptor agonists. Part 1: Lead discovery via encoded combinatorial synthesis

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Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis

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Follicle-stimulating hormone interacts with exoloop 3 of the receptor

21 January 2018

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Differential Roles of Exoloop 1 of the Human Follicle-stimulating Hormone Receptor in Hormone Binding and Receptor Activation

21 January 2018

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Exons 1-10 of the rat LH receptor encode a high affinity hormone binding site and exon 11 encodes G-protein modulation and a potential second hormone binding site

21 January 2018

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Allosteric modulators of G-protein-coupled receptors

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A novel calcium-sensing receptor antagonist transiently stimulates parathyroid hormone secretion in vivo

21 January 2018

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Structure of human follicle-stimulating hormone in complex with its receptor

21 January 2018

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Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function

21 January 2018

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Pharmacological characterization of soluble human FSH receptor extracellular domain: facilitated secretion by coexpression with FSH.

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A molecular dissection of the glycoprotein hormone receptors.

21 January 2018

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Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

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21 January 2018

Identifiers

DOI

10.1074/JBC.M600601200

1 reference

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18 January 2020

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