Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging (Q33246431)

24 July 2017

Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging (English)

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24 July 2017

5

Yoshikazu Takada

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24 July 2017

Li Peng

1

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24 July 2017

Ruiwu Liu

2

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24 July 2017

Jan Marik

3

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24 July 2017

Xiaobing Wang

4

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24 July 2017

Kit S Lam

6

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24 July 2017

11 June 2006

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24 July 2017

Nature Chemical Biology

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24 July 2017

2

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24 July 2017

7

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24 July 2017

381-389

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https://scigraph.springernature.com/pub.10.1038/nchembio798

24 July 2017

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Peptide-based radiopharmaceuticals: future tools for diagnostic imaging of cancers and other diseases

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Alpha 4 integrin increases anoikis of human osteosarcoma cells

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Fibronectin interaction with α4β1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax

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Integrin-mediated drug resistance in multiple myeloma

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Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia

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Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation

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7 January 2021

Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha 4 beta 1).

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7 January 2021

Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents

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7 January 2021

Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases

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7 January 2021

Bacteriophage display and discovery of peptide leads for drug development

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7 January 2021

Radiolabeled peptides in the diagnosis and therapy of oncological diseases

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7 January 2021

A new type of synthetic peptide library for identifying ligand-binding activity

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7 January 2021

The "One-Bead-One-Compound" Combinatorial Library Method

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7 January 2021

Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity

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7 January 2021

Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform

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7 January 2021

Selection of enantioselective acyl transfer catalysts from a pooled peptide library through a fluorescence-based activity assay: an approach to kinetic resolution of secondary alcohols of broad structural scope

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7 January 2021

A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries

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7 January 2021

A novel and rapid encoding method based on mass spectrometry for "one-bead-one-compound" small molecule combinatorial libraries

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7 January 2021

Solutions for library encoding to create collections of discrete compounds

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7 January 2021

Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses

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7 January 2021

Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human lung carcinoma cells of different histotypes

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7 January 2021

Critical amino acid residues for ligand binding are clustered in a predicted beta-turn of the third N-terminal repeat in the integrin alpha 4 and alpha 5 subunits.

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7 January 2021

Shedding light onto live molecular targets

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7 January 2021

Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands

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7 January 2021

Streptavidin in antibody pretargeting. 4. Site-directed mutation provides evidence that both arginine and lysine residues are involved in kidney localization

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7 January 2021

Identification of potent and novel alpha4beta1 antagonists using in silico screening

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7 January 2021

Integrins: bidirectional, allosteric signaling machines

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7 January 2021

Conformational regulation of integrin structure and function

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7 January 2021

Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide

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7 January 2021

PAMAM dendrimer based macromolecules as improved contrast agents

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7 January 2021

Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity

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7 January 2021

Imaging and dosing in radioimmunotherapy with yttrium 90 ibritumomab tiuxetan (Zevalin).

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7 January 2021

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides

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7 January 2021

Critical threonine and aspartic acid residues within the I domains of beta 2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi

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7 January 2021

Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions

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7 January 2021

Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells

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7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO798

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release_k7gror43ozd3dn2hn6auygr6om

24 July 2017

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Fatcat

https://api.fatcat.wiki/v0/release/k7gror43ozd3dn2hn6auygr6om

24 November 2022

mapped directly with Wikidata item

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