Conducting research in individual patients: lessons learnt from two series of N-of-1 trials (Q33258043)

24 July 2017

title

Conducting research in individual patients: lessons learnt from two series of N-of-1 trials (English)

1 reference

24 July 2017

Anke C M Wegman

1

1 reference

24 July 2017

Daniëlle A W M van der Windt

series ordinal

2

1 reference

24 July 2017

Wim A B Stalman

series ordinal

3

1 reference

24 July 2017

Theo P G M de Vries

series ordinal

4

1 reference

24 July 2017

publication date

19 September 2006

1 reference

24 July 2017

1 reference

24 July 2017

volume

7

1 reference

24 July 2017

page(s)

54

1 reference

Celecoxib compared with sustained-release paracetamol for osteoarthritis: a series of n-of-1 trials.

24 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

An n-of-1 trial service in clinical practice: testing the effectiveness of stimulants for attention-deficit/hyperactivity disorder.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

N-of-1 trials of quinine efficacy in skeletal muscle cramps of the leg

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Using n-of-1 trials as a clinical tool to improve prescribing.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

N-of-1 trials: an opportunity to tailor treatment in individual patients

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Efficacy of temazepam in frequent users: a series of N-of-1 trials

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

n-of-1 randomized controlled trials: an opportunity for complementary and alternative medicine evaluation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Do individualized medication effectiveness tests (n-of-1 trials) change clinical decisions about which drugs to use for osteoarthritis and chronic pain?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Treating nausea and vomiting during pregnancy: case outcome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Switching from NSAIDs to paracetamol: a series of n of 1 trials for individual patients with osteoarthritis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

A patient-specific approach for measuring functional status in low back pain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Theophylline for irreversible chronic airflow limitation: a randomized study comparing n of 1 trials to standard practice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Practical issues in equivalence trials.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Combining single patient (N-of-1) trials to estimate population treatment effects and to evaluate individual patient responses to treatment.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Trials to assess equivalence: the importance of rigorous methods

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

n of 1 trials comparing a non-steroidal anti-inflammatory drug with paracetamol in osteoarthritis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

n of 1 trials in osteoarthritis. Caution in interpretation needed

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Statistics notes: Absence of evidence is not evidence of absence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

A clinician's guide for conducting randomized trials in individual patients

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

The n-of-1 randomized controlled trial: clinical usefulness. Our three-year experience

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Controlled trials in single subjects. 1. Value in clinical medicine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

Dextroamphetamine pilot crossover trials and n of 1 trials in patients with chronic tension-type and migraine headache

14 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

Double-blind methylphenidate trials: practical, useful, and highly endorsed by families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

Single patient (n-of-1) trials with binary treatment preference

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-1 trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

Treatment of nausea and vomiting during pregnancy: presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

Treating nausea and vomiting during pregnancy: case progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

Do n-of-1 trials really tailor treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2296-7-54

The efficacy and cost effectiveness of N of 1 studies with diclofenac compared to standard treatment with nonsteroidal antiinflammatory drugs in osteoarthritis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599734

[The importance of equivalence trials in showing the usefulness of treatments]

31 October 2018

1 reference

12 December 2020

Determining optimal therapy--randomized trials in individual patients

1 reference

12 December 2020

Statistical issues in studies of individual response

1 reference

12 December 2020

Randomization tests for restricted alternating treatments designs

1 reference

12 December 2020

Preliminary experiences with a single-patient trials service in general practice

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2296-7-54

1 reference

Dimensions Publication ID

24 July 2017

0 references

1 reference

24 July 2017

1 reference