Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells. (Q33260827)

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20 December 2019

title

Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells (English)

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Marie-Francoise O'Donohue

20 December 2019

author

5

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20 December 2019

Jean-François Riou

10

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20 December 2019

author name string

Dennis Gomez

1

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20 December 2019

Thomas Wenner

2

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20 December 2019

Bertrand Brassart

3

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20 December 2019

Céline Douarre

4

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20 December 2019

Victoria El Khoury

6

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20 December 2019

Kazuo Shin-Ya

7

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20 December 2019

Hamid Morjani

8

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20 December 2019

Chantal Trentesaux

9

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20 December 2019

language of work or name

English

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publication date

17 October 2006

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Journal of Biological Chemistry

20 December 2019

published in

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20 December 2019

volume

281

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20 December 2019

issue

50

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20 December 2019

page(s)

38721-38729

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Switching and signaling at the telomere

20 December 2019

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T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

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Evidence that exposure of the telomere 3' overhang sequence induces senescence

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Senescence Induced by Altered Telomere State, Not Telomere Loss

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Pot1, the putative telomere end-binding protein in fission yeast and humans

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Human POT1 facilitates telomere elongation by telomerase

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Shelterin: the protein complex that shapes and safeguards human telomeres

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21 January 2018

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Inhibition of telomerase by G-quartet DNA structures

21 January 2018

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Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes

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A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity

21 January 2018

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Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.

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Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways

21 January 2018

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21 January 2018

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21 January 2018

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Interaction of telomestatin with the telomeric single-strand overhang.

21 January 2018

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The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells

21 January 2018

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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M605828200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17050546%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference