Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells (Q33270402)

24 July 2017

title

Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells (English)

1 reference

childhood medulloblastoma

24 July 2017

0 references

1 reference

5

Charles G Eberhart

1 reference

24 July 2017

André O von Bueren

1

1 reference

24 July 2017

Tarek Shalaby

2

1 reference

24 July 2017

Julia Rajtarova

3

1 reference

24 July 2017

Duncan Stearns

4

1 reference

24 July 2017

Lawrence Helson

6

1 reference

24 July 2017

Alexandre Arcaro

7

1 reference

24 July 2017

Michael A Grotzer

8

1 reference

24 July 2017

language of work or name

English

0 references

publication date

25 January 2007

1 reference

24 July 2017

1 reference

24 July 2017

volume

7

1 reference

24 July 2017

page(s)

19

1 reference

c-myc overexpression causes anaplasia in medulloblastoma

24 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Medulloblastoma: signalling a change in treatment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Antitumor activity of bruceantin: an old drug with new promise

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Multiple myeloma regression mediated by bruceantin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

c-MYC: more than just a matter of life and death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

An overview of real-time quantitative PCR: applications to quantify cytokine gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Reversible tumorigenesis by MYC in hematopoietic lineages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Mechanisms of apoptosis by c-Myc

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Expression of the c-Myc protein in childhood medulloblastoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Phase I study on bruceantin administered on a weekly schedule

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Phase II trial of bruceantin in metastatic breast carcinoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

N-myc and c-myc oncogenes amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Reduction to homozygosity and gene amplification in central nervous system primitive neuroectodermal tumors of childhood

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Phase I trial of bruceantin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Initial clinical studies with bruceantin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Antitumor Agents XXXIV: Mechanism of Action of Bruceoside a and Brusatol on Nucleic Acid Metabolism of P‐388 Lymphocytic Leukemia Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Oncogene amplification in medulloblastoma: analysis of a case by comparative genomic hybridization and fluorescence in situ hybridization.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Infrequent p53 gene mutations in medulloblastomas.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

Structure-activity relationships of quassinoids for eukaryotic protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

Brusatol-mediated induction of leukemic cell differentiation and G(1) arrest is associated with down-regulation of c-myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

Loss of caspase-8 mRNA expression is common in childhood primitive neuroectodermal brain tumour/medulloblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

ERK1/2 and MEK1/2 induced by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) early during infection of target cells are essential for expression of viral genes and for establishment of infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas.

21 January 2018

2 references

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

C-MYC expression in medulloblastoma and its prognostic value.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Oncogene amplification in pediatric brain tumors.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Large-cell medulloblastomas. A distinct variant with highly aggressive behavior

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794252

Initiation of the Polypeptide Chain by Reticulocyte Cell-Free Systems. Survey of Different Inhibitors of Translation

31 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-7-19

Prognostic implications of chromosome 17p deletions in human medulloblastomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17254356

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mode of action of the antitumor compound bruceantin, an inhibitor of protein synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17254356

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-7-19

1 reference

Dimensions Publication ID

24 July 2017

0 references

1 reference

24 July 2017

1 reference