Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss (Q33280200)

25 July 2017

Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss (English)

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25 July 2017

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1 reference

Allen Herbst

1

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25 July 2017

Jeong W Pak

2

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25 July 2017

Debbie McKenzie

3

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25 July 2017

Entela Bua

4

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25 July 2017

Marwa Bassiouni

5

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25 July 2017

Judd M Aiken

6

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25 July 2017

language of work or name

English

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publication date

1 March 2007

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The Journals of Gerontology

25 July 2017

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25 July 2017

62

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25 July 2017

3

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25 July 2017

235-245

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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

25 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial threshold effects.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

The genetics and pathology of oxidative phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial diseases in man and mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Sarcopenia: origins and clinical relevance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

A proposed refinement of the mitochondrial free radical theory of aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Detection of deletions in the mitochondrial genome of Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial DNA diseases: histological and cellular studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial role in cell aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Age changes in size and number of muscle fibers in human minor pectoral muscle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

The biologic clock: the mitochondria?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Detection of "deleted" mitochondrial genomes in cytochrome-c oxidase-deficient muscle fibers of a patient with Kearns-Sayre syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Detection of a specific mitochondrial DNA deletion in tissues of older humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Diseases of the mitochondrial DNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846622

Mitochondrial diseases: clinical considerations

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FGERONA%2F62.3.235

Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FGERONA%2F62.3.235

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FGERONA%2F62.3.235

Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys.

21 January 2018

1 reference

12 December 2020

Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle

1 reference

12 December 2020

Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA

1 reference

12 December 2020

Multiple age-associated mitochondrial DNA deletions in skeletal muscle of mice

1 reference

12 December 2020

High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys

1 reference

12 December 2020

Functional and metabolic consequences of sarcopenia

1 reference

12 December 2020

Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy

1 reference

12 December 2020

Mitochondrial gene mutation: the ageing process and degenerative diseases

1 reference

12 December 2020

Mitochondrial DNA deletions and cytochrome c oxidase deficiency in muscle fibres

1 reference

12 December 2020

Accumulation of deletions in human mitochondrial DNA during normal aging: analysis by quantitative PCR

1 reference

12 December 2020

Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly

1 reference

12 December 2020

Molecular analysis of the muscle pathology associated with mitochondrial DNA deletions

1 reference

12 December 2020

Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys

1 reference

12 December 2020

Identifiers

DOI

10.1093/GERONA/62.3.235

1 reference

25 July 2017

1 reference

25 July 2017

1 reference