Directed evolution of gene-shuffled IFN-alpha molecules with activity profiles tailored for treatment of chronic viral diseases (Q33284328)

25 July 2017

Directed evolution of gene-shuffled IFN-alpha molecules with activity profiles tailored for treatment of chronic viral diseases (English)

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25 July 2017

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Amy D Brideau-Andersen

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25 July 2017

Xiaojian Huang

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25 July 2017

Siu-Chi Chang Sun

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25 July 2017

Teddy T Chen

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Diane Stark

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Ian J Sas

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Linda Zadik

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Glenn N Dawes

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Douglas R Guptill

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Robert McCord

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Sridhar Govindarajan

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Ajoy Roy

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Shumin Yang

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Judy Gao

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Yong Hong Chen

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Niels Jørgen Ø Skartved

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Annette K Pedersen

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David Lin

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Christopher P Locher

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Indrani Rebbapragada

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Anne Dam Jensen

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Steven H Bass

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Torben L Straight Nissen

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Sridhar Viswanathan

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Graham R Foster

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Julian A Symons

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Phillip A Patten

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language of work or name

English

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publication date

9 May 2007

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Proceedings of the National Academy of Sciences of the United States of America

25 July 2017

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25 July 2017

104

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20

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25 July 2017

8269-8274

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Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta

25 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Hematologic side effects of interferon and ribavirin therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Interferons, interferon-like cytokines, and their receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

A new interferon, limitin, displays equivalent immunomodulatory and antitumor activities without myelosuppressive properties as compared with interferon-alpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Advances in directed protein evolution by recursive genetic recombination: applications to therapeutic proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Evolution of a cytokine using DNA family shuffling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

The structure of eight distinct cloned human leukocyte interferon cDNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

DNA synthesis in nuclei isolated from Daudi B cells: a model to study the antiproliferative mechanisms of interferon-alpha.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0609001104

Peginterferon alone or with ribavirin enhances HCV-specific CD4 T-helper 1 responses in patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0609001104

Mutational analysis of the IFNAR1 binding site on IFNalpha2 reveals the architecture of a weak ligand-receptor binding-site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0609001104

Intracellular signal transduction of interferon on the suppression of haematopoietic progenitor cell growth

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0609001104

The role of Stat4 in species-specific regulation of Th cell development by type I IFNs.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895939

Human T cells elicit IFN-alpha secretion from dendritic cells following cell to cell interactions

31 October 2018

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12 December 2020

IFN-alpha subtypes differentially affect human T cell motility

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12 December 2020

Human type I interferons differ greatly in their effects on the proliferation of primary B cells

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12 December 2020

56 A convenient and rapid cytopathic effect inhibition assay for interferon

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0609001104

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25 July 2017

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25 July 2017

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