Three-dimensional culturing of the Hodgkin lymphoma cell-line L1236 induces a HL tissue-like gene expression pattern (Q33301651)

25 July 2017

title

Three-dimensional culturing of the Hodgkin lymphoma cell-line L1236 induces a HL tissue-like gene expression pattern (English)

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25 July 2017

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Wenbin Wei

6

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author name string

Anna Birgersdotter

1

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Karl R N Baumforth

2

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Anna Porwit

3

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Anne Sundblad

4

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Kerstin I Falk

5

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Jan Sjöberg

7

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Paul G Murray

8

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Magnus Björkholm

9

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Ingemar Ernberg

10

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publication date

1 October 2007

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25 July 2017

number of pages

12

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inferred from page(s)

published in

Leukemia & Lymphoma

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volume

48

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issue

10

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page(s)

2042-2053

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25 July 2017

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Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

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Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma.

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Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression

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Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

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Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

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Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

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21 January 2018

Identifiers

DOI

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25 July 2017

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