New inhibitors of ABCG2 identified by high-throughput screening (Q33311099)

25 July 2017

title

New inhibitors of ABCG2 identified by high-throughput screening (English)

1 reference

high-throughput screening

25 July 2017

main subject

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Michael Dean

7

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Rob Robey

object named as

Robert W Robey

2

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Susan E Bates

4

object named as

Susan E Bates

1 reference

25 July 2017

Curtis J Henrich

1

1 reference

25 July 2017

Heidi R Bokesch

3

1 reference

25 July 2017

Suneet Shukla

5

1 reference

25 July 2017

Suresh V Ambudkar

6

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25 July 2017

James B McMahon

8

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25 July 2017

publication date

1 December 2007

1 reference

Molecular Cancer Therapeutics

25 July 2017

published in

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25 July 2017

volume

6

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25 July 2017

issue

12 Pt 1

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25 July 2017

page(s)

3271-3278

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describes a project that uses

25 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2760480/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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ABCG2: determining its relevance in clinical drug resistance

21 June 2018

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21 June 2018

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The calcium channel blockers, 1,4-dihydropyridines, are substrates of the multidrug resistance-linked ABC drug transporter, ABCG2.

21 June 2018

1 reference

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The prognostic value of P-glycoprotein (ABCB) and breast cancer resistance protein (ABCG2) in adults with de novo acute myeloid leukemia with normal karyotype

21 June 2018

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Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction

21 June 2018

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21 June 2018

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A high-throughput cell-based assay for inhibitors of ABCG2 activity

21 June 2018

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Role of ABCG2/BCRP in biology and medicine

21 June 2018

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MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia

21 June 2018

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21 June 2018

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Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

21 June 2018

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21 June 2018

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BCRP mRNA expression v. clinical outcome in 40 adult AML patients.

21 June 2018

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Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface

21 June 2018

1 reference

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Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice

21 June 2018

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21 June 2018

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Update on NCI in vitro drug screen utilities

21 June 2018

1 reference

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Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

21 June 2018

1 reference

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Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material

21 June 2018

1 reference

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21 June 2018

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21 June 2018

1 reference

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Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer

31 October 2018

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Pheophorbide a is a specific probe for ABCG2 function and inhibition.

31 October 2018

1 reference

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Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

31 October 2018

1 reference

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A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760480

Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18089721

12 December 2020

inferred from PubMed ID database lookup

Using the national cancer institute anticancer drug screen to assess the effect of MRP expression on drug sensitivity profiles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18089721

12 December 2020

inferred from PubMed ID database lookup

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18089721

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1535-7163.MCT-07-0352

1 reference

25 July 2017

1 reference

25 July 2017

1 reference