Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): generation by alternative translation initiation and mRNA splicing (Q33326157)

25 July 2017

title

Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): generation by alternative translation initiation and mRNA splicing (English)

1 reference

25 July 2017

Pankaj Lamba

1

1 reference

25 July 2017

Tord A Hjalt

series ordinal

2

1 reference

25 July 2017

Daniel J Bernard

series ordinal

3

1 reference

25 July 2017

language of work or name

1 reference

28 March 2008

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25 July 2017

published in

BMC Molecular Biology

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25 July 2017

volume

9

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25 July 2017

page(s)

31

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Paired-like homeodomain transcription factors 1 and 2 regulate follicle-stimulating hormone beta-subunit transcription through a conserved cis-element

25 July 2017

cites work

1 reference

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Pituitary transcription factors: from congenital deficiencies to gene therapy

21 June 2018

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21 June 2018

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21 June 2018

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Protein kinase C phosphorylation modulates N- and C-terminal regulatory activities of the PITX2 homeodomain protein

21 June 2018

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Function of alternative splicing

21 June 2018

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21 June 2018

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Essential role of the homeodomain for pituitary homeobox 1 activation of mouse gonadotropin-releasing hormone receptor gene expression through interactions with c-Jun and DNA.

21 June 2018

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Both SMAD2 and SMAD3 mediate activin-stimulated expression of the follicle-stimulating hormone beta subunit in mouse gonadotrope cells

21 June 2018

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PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5.

21 June 2018

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21 June 2018

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Regulation of the rat follicle-stimulating hormone beta-subunit promoter by activin

21 June 2018

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Pushing the limits of the scanning mechanism for initiation of translation

21 June 2018

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Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: An approach using Pitx2 mutants

21 June 2018

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21 June 2018

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Differential regulation of gene expression by PITX2 isoforms

21 June 2018

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Regulation of left-right asymmetry by thresholds of Pitx2c activity

21 June 2018

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An isoform-specific inhibitory domain regulates the LHX3 LIM homeodomain factor holoprotein and the production of a functional alternate translation form

21 June 2018

1 reference

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A single Pitx1 binding site is essential for activity of the LHbeta promoter in transgenic mice

21 June 2018

1 reference

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The pitx2 homeobox protein is required early for endoderm formation and nodal signaling. .

21 June 2018

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Analysis of three Ptx2 splice variants on transcriptional activity and differential expression pattern in the brain

21 June 2018

1 reference

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Transcriptional properties of Ptx1 and Ptx2 isoforms

21 June 2018

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The Pitx2 protein in mouse development

21 June 2018

1 reference

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Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms

21 June 2018

1 reference

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Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism

21 June 2018

1 reference

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Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis

21 June 2018

1 reference

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Dosage requirement of Pitx2 for development of multiple organs

21 June 2018

1 reference

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Major Egr3 isoforms are generated via alternate translation start sites and differ in their abilities to activate transcription

21 June 2018

1 reference

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Expression of the members of the Ptx family of transcription factors in human pituitary adenomas

21 June 2018

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Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain

21 June 2018

1 reference

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Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Pitx2 determines left-right asymmetry of internal organs in vertebrates.

21 June 2018

1 reference

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Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene

21 June 2018

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The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3.

21 June 2018

1 reference

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Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation

21 June 2018

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Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Otlx2, an Otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

The N-end rule: functions, mysteries, uses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

The scanning model for translation: an update

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Alternative translation initiation site usage results in two structurally distinct forms of Pit-1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

More is better: Activators and repressors from the same gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Expression pattern of the homeodomain transcription factor Pitx2 during muscle development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

PITX genes are required for cell survival and Lhx3 activation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Genetic dissection ofPitx2in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Pitx1 and Pitx2 are required for development of hindlimb buds.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

The PTX family of homeodomain transcription factors during pituitary developments.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2330153

Differential expression and functional analysis of Pitx2 isoforms in regulation of heart looping in the chick

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18373856

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18373856

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2199-9-31

1 reference

Dimensions Publication ID

25 July 2017

0 references

1 reference

25 July 2017

1 reference