Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction (Q33332129)

25 July 2017

Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction (English)

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mycobacterium infectious disease

25 July 2017

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7

Gilla Kaplan

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25 July 2017

Elizabeth A Misch

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25 July 2017

Murdo Macdonald

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25 July 2017

Chaman Ranjit

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25 July 2017

Bishwa R Sapkota

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25 July 2017

Richard D Wells

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25 July 2017

M Ruby Siddiqui

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25 July 2017

Thomas R Hawn

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25 July 2017

language of work or name

English

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publication date

7 May 2008

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PLoS Neglected Tropical Diseases

25 July 2017

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e231

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Creative Commons Attribution 2.5 Generic

25 July 2017

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on focus list of Wikimedia project

ScienceSource

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cites work

Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy

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The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm

14 July 2018

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Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?

14 July 2018

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Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage

14 July 2018

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A common human TLR1 polymorphism regulates the innate immune response to lipopeptides

14 July 2018

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A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis

14 July 2018

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Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

14 July 2018

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Genetic predisposition to leprosy: A major gene reveals novel pathways of immunity to Mycobacterium leprae

14 July 2018

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The continuing challenges of leprosy

14 July 2018

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Genetic susceptibility to mycobacterial disease in humans

14 July 2018

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TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis.

14 July 2018

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TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

14 July 2018

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Genetic dissection of immunity in leprosy

14 July 2018

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Toll-like receptor control of the adaptive immune responses

14 July 2018

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Toll-like receptor pathways in the immune responses to mycobacteria

14 July 2018

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Inferences, questions and possibilities in Toll-like receptor signalling

14 July 2018

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Modulating vaccine responses with dendritic cells and Toll-like receptors

14 July 2018

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Toll-like receptor signalling

14 July 2018

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Toll-like receptors and acquired immunity

14 July 2018

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A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

14 July 2018

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Human genetics of common mycobacterial infections

14 July 2018

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Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling

14 July 2018

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Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling

14 July 2018

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The role of Toll-like receptors in immunity against mycobacterial infection

14 July 2018

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Association of a missense mutation of the laminin alpha2 gene with tuberculoid type of leprosy in Indonesian patients.

14 July 2018

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Genetic dissection of immunity to mycobacteria: the human model

14 July 2018

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Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.

14 July 2018

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

14 July 2018

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Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis

14 July 2018

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Classification of leprosy according to immunity. A five-group system

14 July 2018

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Defining protective responses to pathogens: cytokine profiles in leprosy lesions

14 July 2018

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Stepwise replication identifies a low-producing lymphotoxin-α allele as a major risk factor for early-onset leprosy

14 July 2018

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Age Is an Important Risk Factor for Onset and Sequelae of Reversal Reactions in Vietnamese Patients with Leprosy

21 January 2018

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Activation and regulation of Toll-like receptors 2 and 1 in human leprosy

21 January 2018

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The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease

21 January 2018

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The association between microsatellite polymorphisms in intron II of the human Toll-like receptor 2 gene and tuberculosis among Koreans.

21 January 2018

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Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000231

Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes.

21 January 2018

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Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis

21 January 2018

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A major susceptibility locus for leprosy in India maps to chromosome 10p13

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000231

Role of Tumor Necrosis Factor–α and Interleukin‐10 Promoter Gene Polymorphisms in Leprosy

21 January 2018

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12 December 2020

MALDI-TOF mass spectrometry-based SNP genotyping

1 reference

12 December 2020

1 reference

12 December 2020

Association of vitamin D receptor genotype with leprosy type

1 reference

12 December 2020

Mannan-binding lectin plasma levels in leprosy: deficiency confers protection against the lepromatous but not the tuberculoid forms

1 reference

12 December 2020

Mycobacterium leprae inhibits dendritic cell activation and maturation

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12 December 2020

Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy

1 reference

12 December 2020

10.1371/JOURNAL.PNTD.0000231

Identifiers

DOI

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25 July 2017

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25 July 2017

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