Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF. (Q33352015)

26 July 2017

title

Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF. (English)

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26 July 2017

Richard Marais

6

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Claudia Wellbrock

object named as

Claudia Wellbrock

1

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author name string

Sareena Rana

2

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26 July 2017

Hugh Paterson

3

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26 July 2017

Helen Pickersgill

4

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26 July 2017

Thijn Brummelkamp

5

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26 July 2017

language of work or name

English

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publication date

16 July 2008

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26 July 2017

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26 July 2017

volume

3

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26 July 2017

issue

7

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26 July 2017

page(s)

e2734

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

16 July 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

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MITF: master regulator of melanocyte development and melanoma oncogene

21 June 2018

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Lineage dependency and lineage-survival oncogenes in human cancer

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Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

21 June 2018

1 reference

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

21 June 2018

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Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

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Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

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MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

21 June 2018

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Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

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B-RAF is a therapeutic target in melanoma

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The Brn-2 transcription factor links activated BRAF to melanoma proliferation

21 June 2018

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MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma

21 June 2018

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Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

21 June 2018

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Mutations of the BRAF gene in human cancer

21 June 2018

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The melanocyte-specific isoform of the microphthalmia transcription factor affects the phenotype of human melanoma

21 June 2018

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c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.

21 June 2018

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The Hallmarks of Cancer

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The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells

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Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3.

21 June 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002734

MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002734

Suppression of BRAF(V599E) in human melanoma abrogates transformation

21 January 2018

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12 December 2020

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

1 reference

12 December 2020

Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma

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12 December 2020

Micropthalmia transcription factor: a new prognostic marker in intermediate-thickness cutaneous malignant melanoma

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0002734

Identifiers

DOI

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26 July 2017

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26 July 2017

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