Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans (Q33356608)

26 July 2017

Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans (English)

1 reference

26 July 2017

0 references

Luke Norton

3

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Ralph A. DeFronzo

series ordinal

2

object named as

Ralph A DeFronzo

1 reference

26 July 2017

Muhammad A Abdul-Ghani

series ordinal

1

1 reference

PubMed ID

24065789

26 July 2017

language of work or name

English

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publication date

1 October 2013

1 reference

26 July 2017

1 reference

26 July 2017

62

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26 July 2017

3324-3328

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26 July 2017

10

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

26 July 2017

start time

28 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Effects of 24-week treatment with acarbose on glucagon-like peptide 1 in newly diagnosed type 2 diabetic patients: a preliminary report

1 reference

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Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: results of a randomized, placebo-controlled study

14 July 2018

1 reference

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Selective SGLT2 inhibition by tofogliflozin reduces renal glucose reabsorption under hyperglycemic but not under hypo- or euglycemic conditions in rats.

14 July 2018

1 reference

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Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3781482

Why Do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3781482

LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial.

14 July 2018

1 reference

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Efficacy and safety of SGLT2 inhibitors in the treatment of type 2 diabetes mellitus

14 July 2018

1 reference

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Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes.

14 July 2018

1 reference

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Biology of human sodium glucose transporters

14 July 2018

1 reference

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Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

14 July 2018

1 reference

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SGLT2 mediates glucose reabsorption in the early proximal tubule.

14 July 2018

1 reference

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Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial

14 July 2018

1 reference

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Is glycemic control improving in U.S. adults?

14 July 2018

1 reference

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Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose

14 July 2018

1 reference

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

14 July 2018

1 reference

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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

14 July 2018

1 reference

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LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose

14 July 2018

1 reference

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Improved glycemic control in mice lacking Sglt1 and Sglt2.

31 October 2018

1 reference

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Dapagliflozin treatment in patients with different stages of type 2 diabetes mellitus: effects on glycaemic control and body weight

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3781482

Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3781482

Differences in active and passive glucose transport along the proximal nephron

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3781482

Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24065789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Low-dose acarbose does not delay digestion of starch but reduces its bioavailability

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24065789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB13-0604

1 reference

26 July 2017

1 reference

26 July 2017

1 reference

PubMed ID

24065789