Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome (Q33357218)

26 July 2017

Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome (English)

1 reference

26 July 2017

Leana S Wen

11

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Guido Filler

object named as

Guido Filler

9

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Judith A Goodship

4

object named as

Judith A Goodship

1 reference

26 July 2017

13

Timothy H J Goodship

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26 July 2017

3

M Kathryn Liszewski

1 reference

26 July 2017

12

John P Atkinson

1 reference

26 July 2017

Anna Richards

1

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26 July 2017

Elizabeth J Kemp

2

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26 July 2017

Anne K Lampe

5

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26 July 2017

Ronny Decorte

6

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26 July 2017

M Hamza Müslümanoğlu

7

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26 July 2017

Salih Kavukcu

8

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26 July 2017

Yves Pirson

10

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26 July 2017

language of work or name

English

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publication date

17 October 2003

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26 July 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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26 July 2017

100

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26 July 2017

12966-12971

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26 July 2017

22

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Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Cutting edge: localization of the host recognition functions of complement factor H at the carboxyl-terminal: implications for hemolytic uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Post-transplant hemolytic-uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

The genetics and pathogenesis of haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Molecular modelling of the C-terminal domains of factor H of human complement: a correlation between haemolytic uraemic syndrome and a predicted heparin binding site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Targeting complement in therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Membrane cofactor protein (MCP; CD46): isoform-specific tyrosine phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Genetic studies into inherited and sporadic hemolytic uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Control of the complement system.

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

21 June 2018

https://api.crossref.org/works/10.1073%2FPNAS.2135497100

Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Hemolytic uremic syndrome in three adult siblings: a familial study and evolution.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Biochemical characterization of membrane cofactor protein of the complement system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Functional properties of membrane cofactor protein of complement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Membrane cofactor protein of complement is present on human fibroblast, epithelial, and endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Thrombotic Microangiopathies

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2135497100

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2135497100

Identification and characterization of membrane cofactor protein (CD46) in the human kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2135497100

Identification and quantification of complement regulator CD46 on normal human tissues

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240728

Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46)

31 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2135497100

Membrane defenses against attack by complement and perforins

21 January 2018

1 reference

12 December 2020

Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysis

1 reference

12 December 2020

Immunohistochemical demonstration of membrane cofactor protein (MCP) of complement in normal and diseased kidney tissues

1 reference

12 December 2020

Membrane cofactor protein (CD46) of complement. Processing differences related to alternatively spliced cytoplasmic domains

1 reference

12 December 2020

Localization of the complement regulatory proteins in the normal human kidney

1 reference

12 December 2020

Identification of the second heparin-binding domain in human complement factor H

1 reference

12 December 2020

Membrane cofactor protein: importance of N- and O-glycosylation for complement regulatory function

1 reference

12 December 2020

Control of C3b and C5b deposition by CD46 (membrane cofactor protein) after alternative but not classical complement activation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.2135497100

1 reference

26 July 2017

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26 July 2017

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