Phase I and pharmacokinetic (PK) study of MAG-CPT (PNU 166148): a polymeric derivative of camptothecin (CPT) (Q33361186)

26 July 2017

Phase I and pharmacokinetic (PK) study of MAG-CPT (PNU 166148): a polymeric derivative of camptothecin (CPT) (English)

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26 July 2017

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D Bissett

1

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26 July 2017

J Cassidy

2

1 reference

26 July 2017

J S de Bono

3

1 reference

26 July 2017

F Muirhead

4

1 reference

26 July 2017

M Main

5

1 reference

26 July 2017

L Robson

6

1 reference

26 July 2017

D Fraier

7

1 reference

26 July 2017

M L Magnè

8

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26 July 2017

C Pellizzoni

9

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26 July 2017

M G Porro

10

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26 July 2017

R Spinelli

11

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26 July 2017

W Speed

12

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26 July 2017

C Twelves

13

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26 July 2017

language of work or name

English

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publication date

1 July 2004

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British Journal of Cancer

26 July 2017

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26 July 2017

91

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26 July 2017

50-55

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26 July 2017

1

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601922

26 July 2017

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cites work

Assessment of normal and tumor tissue uptake of MAG-CPT, a polymer-bound prodrug of camptothecin, in patients undergoing elective surgery for colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Cancer Research Campaign Phase I/II Committee

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Molecular, cellular, and clinical aspects of the pharmacology of 20(S)camptothecin and its derivatives.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): correlation with preclinical studies.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Passive tumor targeting of soluble macromolecules and drug conjugates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601922

High-performance liquid chromatographic analysis for the determination of a novel polymer-bound camptothecin derivative (MAG-camptothecin) and free camptothecin in human plasma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364737

Polymer-bound camptothecin: initial biodistribution and antitumour activity studies

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15187995

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Camptothecin delivery systems: the utility of amino acid spacers for the conjugation of camptothecin with polyethylene glycol to create prodrugs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15187995

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15187995

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6601922

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Dimensions Publication ID

26 July 2017

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26 July 2017

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