Binomial mitotic segregation of MYCN-carrying double minutes in neuroblastoma illustrates the role of randomness in oncogene amplification (Q33366575)

26 July 2017

Binomial mitotic segregation of MYCN-carrying double minutes in neuroblastoma illustrates the role of randomness in oncogene amplification (English)

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26 July 2017

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Gisela Lundberg

1

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26 July 2017

Anders H Rosengren

2

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26 July 2017

Ulf Håkanson

3

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26 July 2017

Henrik Stewénius

4

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26 July 2017

Yuesheng Jin

5

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26 July 2017

Ylva Stewénius

6

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26 July 2017

Sven Påhlman

7

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26 July 2017

David Gisselsson

8

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26 July 2017

language of work or name

English

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publication date

29 August 2008

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26 July 2017

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26 July 2017

3

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26 July 2017

8

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26 July 2017

e3099

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Creative Commons Attribution 4.0 International

26 July 2017

start time

29 August 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Clinical significance of MYCN amplification and ploidy in favorable-stage neuroblastoma: a report from the Children's Oncology Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Distinct mitotic segregation errors mediate chromosomal instability in aggressive urothelial cancers.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Induction of senescence in MYCN amplified neuroblastoma cell lines by hydroxyurea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

The MYCN enigma: significance of MYCN expression in neuroblastoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Neuroblastoma: biological insights into a clinical enigma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Radiation therapy depletes extrachromosomally amplified drug resistance genes and oncogenes from tumor cells via micronuclear capture of episomes and double minute chromosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Refined characterisation of chromosome aberrations in tumours by multicolour banding and electronic mapping resources

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

The dynamics of acentric chromosomes in cancer cells revealed by GFP-based chromosome labeling strategies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Topology of double minutes (dmins) and homogeneously staining regions (HSRs) in nuclei of human neuroblastoma cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Involvement of 14-3-3 proteins in nuclear localization of telomerase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Multiple pathways to cellular senescence: role of telomerase repressors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Heterogeneity in telomere length of human chromosomes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Double minutes in human tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Augmented MYCN expression advances the malignant phenotype of human neuroblastoma cells: evidence for induction of autocrine growth factor activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Double minute chromosomes in mouse methotrexate-resistant cells studied by atomic force microscopy.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Telomerase activity by TRAP assay and telomerase RNA (hTR) expression are predictive of outcome in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Study of proliferation and apoptosis in neuroblastoma. Their relation with other prognostic factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Targeted MYCN expression affects cytotoxic potential of chemotherapeutic drugs in neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Mitotic segregation of viral and cellular acentric extrachromosomal molecules by chromosome tethering.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518122

Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma

31 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Does MYCN Amplification Manifested as Homogeneously Staining Regions at Diagnosis Predict a Worse Outcome in Children with Neuroblastoma? A Children's Oncology Group Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003099

Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma

21 January 2018

1 reference

12 December 2020

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

1 reference

12 December 2020

Double minute chromosomes are not centromeric regions of the host chromosomes

1 reference

12 December 2020

Have double minutes functioning centromeres?

1 reference

12 December 2020

Double minutes replicate once during S phase of the cell cycle

1 reference

12 December 2020

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

1 reference

12 December 2020

Analysis of N-myc amplification in relation to disease stage and histologic types in human neuroblastomas

1 reference

12 December 2020

DNA replication-dependent intranuclear relocation of double minute chromatin

1 reference

12 December 2020

Use of chromogenic in situ hybridization to identify MYCN gene copy number in neuroblastoma using routine tissue sections

1 reference

12 December 2020

Origin and functional significance of large-scale chromosomal imbalances in neuroblastoma

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0003099

Identifiers

DOI

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26 July 2017

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26 July 2017

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