Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses. (Q33366578)

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English	Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses.	scientific article

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13 January 2020

Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses (English)

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13 January 2020

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13 January 2020

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Qian-Jin Zhang

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13 January 2020

Xiao-Lin Li

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13 January 2020

David Wang

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13 January 2020

Xiao-Cong Huang

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13 January 2020

J Michael Mathis

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13 January 2020

Wei-Ming Duan

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13 January 2020

David Knight

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13 January 2020

Runhua Shi

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13 January 2020

Jonathan Glass

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13 January 2020

Dong-Qing Zhang

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13 January 2020

Wilfred A Jefferies

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29 August 2008

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13 January 2020

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13 January 2020

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13 January 2020

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13 January 2020

e3097

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13 January 2020

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Creative Commons Attribution 4.0 International

29 August 2008

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TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma

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Using the TAP component of the antigen-processing machinery as a molecular adjuvant

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Restoration of the expression of transporters associated with antigen processing in lung carcinoma increases tumor-specific immune responses and survival

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T cell activation correlates with an increased proportion of antigen among the materials acquired from target cells

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Tumor-derived heat shock protein 70-pulsed dendritic cells elicit tumor-specific cytotoxic T lymphocytes (CTLs) and tumor immunity

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Correction of Defects Responsible for Impaired Qa-2 Class Ib MHC Expression on Melanoma Cells Protects Mice from Tumor Growth

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Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells.

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Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6.

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Selective export of MHC class I molecules from the ER after their dissociation from TAP

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Antigen-processing machinery breakdown and tumor growth

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The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice

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Deficiency of transporter for antigen presentation (TAP) in tumor cells allows evasion of immune surveillance and increases tumorigenesis.

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A critical contemplation on the role of heat shock proteins in transfer of antigenic peptides during antigen presentation

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Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but not carboxyl-terminus of the peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18769733

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0003097

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13 January 2020

2008PLoSO...3.3097Z

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13 January 2020

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13 January 2020

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